Chemoradiation for Olfactory Neuroblastoma
Olfactory neuroblastoma is a rare intranasal tumor, and the standard treatment for this disease remains controversial. Some clinicians contend that a combination of surgery and radiotherapy is the most efficacious approach, which frequently has a good prognosis. Chemotherapy is often reserved for th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-03-01
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| Series: | Journal of Cancer Research and Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2311300616300593 |
| _version_ | 1819237397012938752 |
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| author | Sheun-Ru Yang Yuan-Hua Wu Chia-Jui Yen |
| author_facet | Sheun-Ru Yang Yuan-Hua Wu Chia-Jui Yen |
| author_sort | Sheun-Ru Yang |
| collection | DOAJ |
| description | Olfactory neuroblastoma is a rare intranasal tumor, and the standard treatment for this disease remains controversial. Some clinicians contend that a combination of surgery and radiotherapy is the most efficacious approach, which frequently has a good prognosis. Chemotherapy is often reserved for those patients with tumor recurrence and distant metastasis. Regarding such metastasis, it is well-known that cervical metastasis indicates poor prognosis. We presented a 36-year-old woman who was diagnosed with a neuroblastoma with neck lymph node metastasis who did not undergo surgery. We treated her with chemotherapy followed by concurrent chemoradiation, and the result showed good response without sequela. We also reviewed the literature regarding the chemotherapy of olfactory neuroblastoma. In conclusion, olfactory neuroblastoma is highly sensitive to chemotherapy. However, long-term surveillanceof patients should be maintained in the event of local recurrence and distant metastasis. |
| first_indexed | 2024-12-23T13:19:40Z |
| format | Article |
| id | doaj.art-2dd6b418da9a437a87f86070d17b9e82 |
| institution | Directory Open Access Journal |
| issn | 2311-3006 |
| language | English |
| last_indexed | 2024-12-23T13:19:40Z |
| publishDate | 2015-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj.art-2dd6b418da9a437a87f86070d17b9e822022-12-21T17:45:29ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062015-03-0121495510.6323/JCRP.2015.2.1.06Chemoradiation for Olfactory NeuroblastomaSheun-Ru Yang0Yuan-Hua Wu1Chia-Jui Yen2Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDepartment of Radiation Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDivision of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanOlfactory neuroblastoma is a rare intranasal tumor, and the standard treatment for this disease remains controversial. Some clinicians contend that a combination of surgery and radiotherapy is the most efficacious approach, which frequently has a good prognosis. Chemotherapy is often reserved for those patients with tumor recurrence and distant metastasis. Regarding such metastasis, it is well-known that cervical metastasis indicates poor prognosis. We presented a 36-year-old woman who was diagnosed with a neuroblastoma with neck lymph node metastasis who did not undergo surgery. We treated her with chemotherapy followed by concurrent chemoradiation, and the result showed good response without sequela. We also reviewed the literature regarding the chemotherapy of olfactory neuroblastoma. In conclusion, olfactory neuroblastoma is highly sensitive to chemotherapy. However, long-term surveillanceof patients should be maintained in the event of local recurrence and distant metastasis.http://www.sciencedirect.com/science/article/pii/S2311300616300593olfactoryneuroblastomachemotherapyradiotherapy |
| spellingShingle | Sheun-Ru Yang Yuan-Hua Wu Chia-Jui Yen Chemoradiation for Olfactory Neuroblastoma Journal of Cancer Research and Practice olfactoryneuroblastoma chemotherapy radiotherapy |
| title | Chemoradiation for Olfactory Neuroblastoma |
| title_full | Chemoradiation for Olfactory Neuroblastoma |
| title_fullStr | Chemoradiation for Olfactory Neuroblastoma |
| title_full_unstemmed | Chemoradiation for Olfactory Neuroblastoma |
| title_short | Chemoradiation for Olfactory Neuroblastoma |
| title_sort | chemoradiation for olfactory neuroblastoma |
| topic | olfactoryneuroblastoma chemotherapy radiotherapy |
| url | http://www.sciencedirect.com/science/article/pii/S2311300616300593 |
| work_keys_str_mv | AT sheunruyang chemoradiationforolfactoryneuroblastoma AT yuanhuawu chemoradiationforolfactoryneuroblastoma AT chiajuiyen chemoradiationforolfactoryneuroblastoma |