A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy
Abstract Empathy is defined as the ability to vicariously experience others’ suffering (vicarious pain) or feeling their joy (vicarious reward). While most neuroimaging studies have focused on vicarious pain and describe similar neural responses during the observed and the personal negative affectiv...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-18911-4 |
| _version_ | 1811182266535116800 |
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| author | J. Toppi M. Siniatchkin P. Vogel C. M. Freitag L. Astolfi A. Ciaramidaro |
| author_facet | J. Toppi M. Siniatchkin P. Vogel C. M. Freitag L. Astolfi A. Ciaramidaro |
| author_sort | J. Toppi |
| collection | DOAJ |
| description | Abstract Empathy is defined as the ability to vicariously experience others’ suffering (vicarious pain) or feeling their joy (vicarious reward). While most neuroimaging studies have focused on vicarious pain and describe similar neural responses during the observed and the personal negative affective involvement, only initial evidence has been reported for the neural responses to others’ rewards and positive empathy. Here, we propose a novel approach, based on the simultaneous recording of multi-subject EEG signals and exploiting the wavelet coherence decomposition to measure the temporal alignment between ERPs in a dyad of interacting subjects. We used the Third-Party Punishment (TPP) paradigm to elicit the personal and vicarious experiences. During a positive experience, we observed the simultaneous presence in both agents of the Late Positive Potential (LPP), an ERP component related to emotion processing, as well as the existence of an inter-subject ERPs synchronization in the related time window. Moreover, the amplitude of the LPP synchronization was modulated by the presence of a human-agent. Finally, the localized brain circuits subtending the ERP-synchronization correspond to key-regions of personal and vicarious reward. Our findings suggest that the temporal and spatial ERPs alignment might be a novel and direct proxy measure of empathy. |
| first_indexed | 2024-04-11T09:29:54Z |
| format | Article |
| id | doaj.art-2dd6e6bbc8774d72a2ec0d4d96971f9b |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T09:29:54Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-2dd6e6bbc8774d72a2ec0d4d96971f9b2022-12-22T04:31:55ZengNature PortfolioScientific Reports2045-23222022-10-0112111210.1038/s41598-022-18911-4A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathyJ. Toppi0M. Siniatchkin1P. Vogel2C. M. Freitag3L. Astolfi4A. Ciaramidaro5Department of Computer, Control and Management Engineering A. Ruberti, Sapienza University of RomeDepartment of Child and Adolescent Psychiatry and Psychotherapy, Protestant Hospital Bethel, University Clinics OWL, Campus Bethel, Bielefeld UniversityDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe UniversityDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe UniversityDepartment of Computer, Control and Management Engineering A. Ruberti, Sapienza University of RomeDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe UniversityAbstract Empathy is defined as the ability to vicariously experience others’ suffering (vicarious pain) or feeling their joy (vicarious reward). While most neuroimaging studies have focused on vicarious pain and describe similar neural responses during the observed and the personal negative affective involvement, only initial evidence has been reported for the neural responses to others’ rewards and positive empathy. Here, we propose a novel approach, based on the simultaneous recording of multi-subject EEG signals and exploiting the wavelet coherence decomposition to measure the temporal alignment between ERPs in a dyad of interacting subjects. We used the Third-Party Punishment (TPP) paradigm to elicit the personal and vicarious experiences. During a positive experience, we observed the simultaneous presence in both agents of the Late Positive Potential (LPP), an ERP component related to emotion processing, as well as the existence of an inter-subject ERPs synchronization in the related time window. Moreover, the amplitude of the LPP synchronization was modulated by the presence of a human-agent. Finally, the localized brain circuits subtending the ERP-synchronization correspond to key-regions of personal and vicarious reward. Our findings suggest that the temporal and spatial ERPs alignment might be a novel and direct proxy measure of empathy.https://doi.org/10.1038/s41598-022-18911-4 |
| spellingShingle | J. Toppi M. Siniatchkin P. Vogel C. M. Freitag L. Astolfi A. Ciaramidaro A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy Scientific Reports |
| title | A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy |
| title_full | A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy |
| title_fullStr | A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy |
| title_full_unstemmed | A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy |
| title_short | A novel approach to measure brain-to-brain spatial and temporal alignment during positive empathy |
| title_sort | novel approach to measure brain to brain spatial and temporal alignment during positive empathy |
| url | https://doi.org/10.1038/s41598-022-18911-4 |
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