Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis

Background: Since the introduction of cognitive behaviour therapy (CBT), researchers are searching for the optimum schedule of sessions to maximize the effectiveness. In the last decades, intensive treatments - multiple long sessions in a few weeks - became popular in patients with anxiety disorders...

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Main Authors: Karin C.P. Remmerswaal, Luuk Lans, Adrie Seldenrijk, Adriaan W. Hoogendoorn, Anton J.L.M. van Balkom, Neeltje M. Batelaan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Affective Disorders Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915321001839
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author Karin C.P. Remmerswaal
Luuk Lans
Adrie Seldenrijk
Adriaan W. Hoogendoorn
Anton J.L.M. van Balkom
Neeltje M. Batelaan
author_facet Karin C.P. Remmerswaal
Luuk Lans
Adrie Seldenrijk
Adriaan W. Hoogendoorn
Anton J.L.M. van Balkom
Neeltje M. Batelaan
author_sort Karin C.P. Remmerswaal
collection DOAJ
description Background: Since the introduction of cognitive behaviour therapy (CBT), researchers are searching for the optimum schedule of sessions to maximize the effectiveness. In the last decades, intensive treatments - multiple long sessions in a few weeks - became popular in patients with anxiety disorders and obsessive-compulsive disorder (OCD). However, it is still unknown whether intensive CBT is superior to regular CBT (short weekly sessions for several months). Methods: This meta-analysis examined whether intensive CBT is superior to regular CBT in patients with anxiety disorders and OCD in reducing anxiety, obsessive-compulsive (OC) and comorbid depressive symptoms, and in reducing dropout. A systematic literature search was performed in PubMed, PsycINFO and Embase in which words indicative of an anxiety disorder or OCD were combined with intensive treatment and CBT. Results: We identified 5012 unique studies. Two randomised controlled trials (RCTs) and four non-RCTs were included, pertaining to 393 subjects. Intensive CBT and regular CBT did not statistically differ in reducing anxiety or OC symptoms from pre- to post-treatment and from post-treatment to follow-up. However, intensive CBT was significantly better in reducing depressive symptoms from pre- to post-treatment (g = 0.25; 95% CI: (0.04, 0.45)). Dropout was only reported in two studies and could thus not be meta-analysed. Limitations: The included studies were limited in number and quality. Conclusions: High-quality RCTs are needed to assess both effectivity and feasibility of intensive CBT. Meanwhile, intensive CBT might be preferable for patients with comorbid depression or for those needing fast improvement, due to its shorter lead time.
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spelling doaj.art-2ddbc827dbe843ecad4781862109ca4f2022-12-21T19:35:29ZengElsevierJournal of Affective Disorders Reports2666-91532021-12-016100267Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysisKarin C.P. Remmerswaal0Luuk Lans1Adrie Seldenrijk2Adriaan W. Hoogendoorn3Anton J.L.M. van Balkom4Neeltje M. Batelaan5Corresponding author.; Amsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsAmsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsAmsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsAmsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsAmsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsAmsterdam UMC, location VUMC, Department of Psychiatry, Amsterdam Public Health Institute and GGZ inGeest Specialized Mental Health Care, Amsterdam, the NetherlandsBackground: Since the introduction of cognitive behaviour therapy (CBT), researchers are searching for the optimum schedule of sessions to maximize the effectiveness. In the last decades, intensive treatments - multiple long sessions in a few weeks - became popular in patients with anxiety disorders and obsessive-compulsive disorder (OCD). However, it is still unknown whether intensive CBT is superior to regular CBT (short weekly sessions for several months). Methods: This meta-analysis examined whether intensive CBT is superior to regular CBT in patients with anxiety disorders and OCD in reducing anxiety, obsessive-compulsive (OC) and comorbid depressive symptoms, and in reducing dropout. A systematic literature search was performed in PubMed, PsycINFO and Embase in which words indicative of an anxiety disorder or OCD were combined with intensive treatment and CBT. Results: We identified 5012 unique studies. Two randomised controlled trials (RCTs) and four non-RCTs were included, pertaining to 393 subjects. Intensive CBT and regular CBT did not statistically differ in reducing anxiety or OC symptoms from pre- to post-treatment and from post-treatment to follow-up. However, intensive CBT was significantly better in reducing depressive symptoms from pre- to post-treatment (g = 0.25; 95% CI: (0.04, 0.45)). Dropout was only reported in two studies and could thus not be meta-analysed. Limitations: The included studies were limited in number and quality. Conclusions: High-quality RCTs are needed to assess both effectivity and feasibility of intensive CBT. Meanwhile, intensive CBT might be preferable for patients with comorbid depression or for those needing fast improvement, due to its shorter lead time.http://www.sciencedirect.com/science/article/pii/S2666915321001839Meta-analysisAnxiety disorderOCDIntensive CBTMassed CBT
spellingShingle Karin C.P. Remmerswaal
Luuk Lans
Adrie Seldenrijk
Adriaan W. Hoogendoorn
Anton J.L.M. van Balkom
Neeltje M. Batelaan
Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
Journal of Affective Disorders Reports
Meta-analysis
Anxiety disorder
OCD
Intensive CBT
Massed CBT
title Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
title_full Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
title_fullStr Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
title_full_unstemmed Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
title_short Effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive-compulsive disorders: A meta-analysis
title_sort effectiveness and feasibility of intensive versus regular cognitive behaviour therapy in patients with anxiety and obsessive compulsive disorders a meta analysis
topic Meta-analysis
Anxiety disorder
OCD
Intensive CBT
Massed CBT
url http://www.sciencedirect.com/science/article/pii/S2666915321001839
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