An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva
Saliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-03-01
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| Series: | Nanomaterials |
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| Online Access: | http://www.mdpi.com/2079-4991/7/3/67 |
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| author | Chongdai Luo Yangyang Wang Xuemeng Li Xueqin Jiang Panpan Gao Kang Sun Jianhua Zhou Zhiguang Zhang Qing Jiang |
| author_facet | Chongdai Luo Yangyang Wang Xuemeng Li Xueqin Jiang Panpan Gao Kang Sun Jianhua Zhou Zhiguang Zhang Qing Jiang |
| author_sort | Chongdai Luo |
| collection | DOAJ |
| description | Saliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR) substrate composed of polyaniline (PANI)-gold hybrid nanostructures as an optical sensor for monitoring the pH of saliva samples. The overall appearance and topography of the substrates, the composition, and the wettability of the LSPR surfaces were characterized by optical and scanning electron microscope (SEM) images, infrared spectra, and contact angles measurement, respectively. The PANI-gold hybrid substrate readily responded to the pH. The response time was very short, which was 3.5 s when the pH switched from 2 to 7, and 4.5 s from 7 to 2. The changes of visible-near-infrared (NIR) spectra of this sensor upon varying pH in solution showed that—for the absorption at given wavelengths of 665 nm and 785 nm—the sensitivities were 0.0299 a.u./pH (a.u. = arbitrary unit) with a linear range of pH = 5–8 and 0.0234 a.u./pH with linear range of pH = 2–8, respectively. By using this new sensor, the pH of a real saliva sample was monitored and was consistent with the parallel measurements with a standard laboratory method. The results suggest that this novel LSPR sensor shows great potential in the field of mobile healthcare and home medical devices, and could also be modified by different sensitive materials to detect various molecules or ions in the future. |
| first_indexed | 2024-12-13T05:58:08Z |
| format | Article |
| id | doaj.art-2ddc22a42bfa4ee6b4e789047f0e12d2 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-13T05:58:08Z |
| publishDate | 2017-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-2ddc22a42bfa4ee6b4e789047f0e12d22022-12-21T23:57:23ZengMDPI AGNanomaterials2079-49912017-03-01736710.3390/nano7030067nano7030067An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in SalivaChongdai Luo0Yangyang Wang1Xuemeng Li2Xueqin Jiang3Panpan Gao4Kang Sun5Jianhua Zhou6Zhiguang Zhang7Qing Jiang8Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaDepartment of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Engineering, Sun Yat-sen University, Guangzhou 510275, ChinaSaliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR) substrate composed of polyaniline (PANI)-gold hybrid nanostructures as an optical sensor for monitoring the pH of saliva samples. The overall appearance and topography of the substrates, the composition, and the wettability of the LSPR surfaces were characterized by optical and scanning electron microscope (SEM) images, infrared spectra, and contact angles measurement, respectively. The PANI-gold hybrid substrate readily responded to the pH. The response time was very short, which was 3.5 s when the pH switched from 2 to 7, and 4.5 s from 7 to 2. The changes of visible-near-infrared (NIR) spectra of this sensor upon varying pH in solution showed that—for the absorption at given wavelengths of 665 nm and 785 nm—the sensitivities were 0.0299 a.u./pH (a.u. = arbitrary unit) with a linear range of pH = 5–8 and 0.0234 a.u./pH with linear range of pH = 2–8, respectively. By using this new sensor, the pH of a real saliva sample was monitored and was consistent with the parallel measurements with a standard laboratory method. The results suggest that this novel LSPR sensor shows great potential in the field of mobile healthcare and home medical devices, and could also be modified by different sensitive materials to detect various molecules or ions in the future.http://www.mdpi.com/2079-4991/7/3/67optical sensorhybrid nanostructureslocalized surface plasmon resonancepHsaliva |
| spellingShingle | Chongdai Luo Yangyang Wang Xuemeng Li Xueqin Jiang Panpan Gao Kang Sun Jianhua Zhou Zhiguang Zhang Qing Jiang An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva Nanomaterials optical sensor hybrid nanostructures localized surface plasmon resonance pH saliva |
| title | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
| title_full | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
| title_fullStr | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
| title_full_unstemmed | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
| title_short | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
| title_sort | optical sensor with polyaniline gold hybrid nanostructures for monitoring ph in saliva |
| topic | optical sensor hybrid nanostructures localized surface plasmon resonance pH saliva |
| url | http://www.mdpi.com/2079-4991/7/3/67 |
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