Relationship between XPD, RAD51, and APEX1 DNA repair genotypes and prostate cancer risk in the male population of Rio de Janeiro, Brazil

Relationship between XPD, RAD51, and APEX1 DNA repair genotypes and prostate cancer risk in the male population of Rio de Janeiro, Brazil

Abstract Susceptibility to cancer ensues in individuals carrying malfunctioning DNA repair mechanisms. The impact of Single Nucleotide Polymorphisms (SNPs) in key DNA repair mechanisms on risk for prostate cancer was investigated in this case-control study. Samples consisted of 110 patients with con...

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Bibliographic Details
Main Authors: Ana Sheila Cypriano, Gilda Alves, Antonio Augusto Ornellas, José Scheinkman, Renata Almeida, Luciano Scherrer, Claudia Lage
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2017-11-01
Series:Genetics and Molecular Biology
Subjects:
Prostate cancer
single nucleotide polymorphism
XPD
DNA repair
gene-environment interaction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017005027105&lng=en&tlng=en

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