The Commonality and Individuality of Human Brains When Performing Tasks
It is imperative to study individual brain functioning toward understanding the neural bases responsible for individual behavioral and clinical traits. The complex and dynamic brain activity varies from area to area and from time to time across the entire brain, and BOLD-fMRI measures this spatiotem...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/14/2/125 |
| _version_ | 1797298745142935552 |
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| author | Jie Huang |
| author_facet | Jie Huang |
| author_sort | Jie Huang |
| collection | DOAJ |
| description | It is imperative to study individual brain functioning toward understanding the neural bases responsible for individual behavioral and clinical traits. The complex and dynamic brain activity varies from area to area and from time to time across the entire brain, and BOLD-fMRI measures this spatiotemporal activity at large-scale systems level. We present a novel method to investigate task-evoked whole brain activity that varies not only from person to person but also from task trial to trial within each task type, offering a means of characterizing the individuality of human brains when performing tasks. For each task trial, the temporal correlation of task-evoked ideal time signal with the time signal of every point in the brain yields a full spatial map that characterizes the whole brain’s functional co-activity (FC) relative to the task-evoked ideal response. For any two task trials, regardless of whether they are the same task or not, the spatial correlation of their corresponding two FC maps over the entire brain quantifies the similarity between these two maps, offering a means of investigating the variation in the whole brain activity trial to trial. The results demonstrated a substantially varied whole brain activity from trial to trial for each task category. The degree of this variation was task type-dependent and varied from subject to subject, showing a remarkable individuality of human brains when performing tasks. It demonstrates the potential of using the presented method to investigate the relationship of the whole brain activity with individual behavioral and clinical traits. |
| first_indexed | 2024-03-07T22:39:26Z |
| format | Article |
| id | doaj.art-2de65c50b3f34a3fa2a7eb0b36c1c10d |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-07T22:39:26Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-2de65c50b3f34a3fa2a7eb0b36c1c10d2024-02-23T15:09:39ZengMDPI AGBrain Sciences2076-34252024-01-0114212510.3390/brainsci14020125The Commonality and Individuality of Human Brains When Performing TasksJie Huang0Department of Radiology, Michigan State University, East Lansing, MI 48824, USAIt is imperative to study individual brain functioning toward understanding the neural bases responsible for individual behavioral and clinical traits. The complex and dynamic brain activity varies from area to area and from time to time across the entire brain, and BOLD-fMRI measures this spatiotemporal activity at large-scale systems level. We present a novel method to investigate task-evoked whole brain activity that varies not only from person to person but also from task trial to trial within each task type, offering a means of characterizing the individuality of human brains when performing tasks. For each task trial, the temporal correlation of task-evoked ideal time signal with the time signal of every point in the brain yields a full spatial map that characterizes the whole brain’s functional co-activity (FC) relative to the task-evoked ideal response. For any two task trials, regardless of whether they are the same task or not, the spatial correlation of their corresponding two FC maps over the entire brain quantifies the similarity between these two maps, offering a means of investigating the variation in the whole brain activity trial to trial. The results demonstrated a substantially varied whole brain activity from trial to trial for each task category. The degree of this variation was task type-dependent and varied from subject to subject, showing a remarkable individuality of human brains when performing tasks. It demonstrates the potential of using the presented method to investigate the relationship of the whole brain activity with individual behavioral and clinical traits.https://www.mdpi.com/2076-3425/14/2/125human brain functionwhole brain activityindividuality |
| spellingShingle | Jie Huang The Commonality and Individuality of Human Brains When Performing Tasks Brain Sciences human brain function whole brain activity individuality |
| title | The Commonality and Individuality of Human Brains When Performing Tasks |
| title_full | The Commonality and Individuality of Human Brains When Performing Tasks |
| title_fullStr | The Commonality and Individuality of Human Brains When Performing Tasks |
| title_full_unstemmed | The Commonality and Individuality of Human Brains When Performing Tasks |
| title_short | The Commonality and Individuality of Human Brains When Performing Tasks |
| title_sort | commonality and individuality of human brains when performing tasks |
| topic | human brain function whole brain activity individuality |
| url | https://www.mdpi.com/2076-3425/14/2/125 |
| work_keys_str_mv | AT jiehuang thecommonalityandindividualityofhumanbrainswhenperformingtasks AT jiehuang commonalityandindividualityofhumanbrainswhenperformingtasks |