Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis

Systemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case...

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Main Author: Salil Mehta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=Mehta
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author Salil Mehta
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description Systemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case 1: A 38-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active supraclavicular and chest lymph nodes. An aspiration cytology of the cervical lymph node revealed caseating granulomas suggestive of tuberculosis. Case 2: A 58-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active lymph nodes in the neck. A biopsy of the cervical lymph node revealed epithelioid granulomas suggestive of tuberculosis. Both patients were started on standard antitubercular therapy with a subsequent marked reduction of activity. PET/CT scans may suggest the sites of safe high-yield biopsies.
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spelling doaj.art-2de986753b354309855d6704c77776a12022-12-22T01:26:02ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-01611060360510.4103/0301-4738.121091Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosisSalil MehtaSystemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case 1: A 38-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active supraclavicular and chest lymph nodes. An aspiration cytology of the cervical lymph node revealed caseating granulomas suggestive of tuberculosis. Case 2: A 58-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active lymph nodes in the neck. A biopsy of the cervical lymph node revealed epithelioid granulomas suggestive of tuberculosis. Both patients were started on standard antitubercular therapy with a subsequent marked reduction of activity. PET/CT scans may suggest the sites of safe high-yield biopsies.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=MehtaPosterior open globe injuriesposterior to rectus insertionzone III open globe injuriesGlaucoma severityjuvenile glaucomajuvenile-onset primary open angle glaucomavisual field defectsDiabetic retinopathyrenal transplantvisual outcomeGujaratilogMARrepeatabilityvalidityvisual acuityMultiple sclerosisoptic neuritisoptical coherence tomographyretinal nerve fi ber layervisual functionsAxon diameterelectron microscopynerve fiber layeroligodendrocytespathologyFrequency doubling technology perimetrypediatric visual field testingstandard automated perimetryCentral corneal thicknessglaucomapachymetry20G Silicone rodmonocanalicular stentcanalicular laceration repairCoat′s like responsepigmented paravenous chorioretinal atrophyRetinochoroiditis radiataDacryocystectomyoculosporidiosisRhinosporidiumInfectious scleritismicrobial scleritisocular infectionscleritisCongenital ectropioncongenital eyelid imbrication syndromecongenital floppy eyelid syndromecongenital lax upper eyelid syndromedown syndromeInner retinal layer thicknessoptic nerve hypoplasiaouter retinal layer thicknessretinal nerve fiber layer thicknessspectral domain optical coherence tomographyAbducens nerve palsyhyperhomocysteinemiaisolated abducens nerve palsynontraumaticInverted internal limiting membrane flap techniquemacular holemacular hole surgeryOcularpositron emission tomographytuberculosis
spellingShingle Salil Mehta
Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
Indian Journal of Ophthalmology
Posterior open globe injuries
posterior to rectus insertion
zone III open globe injuries
Glaucoma severity
juvenile glaucoma
juvenile-onset primary open angle glaucoma
visual field defects
Diabetic retinopathy
renal transplant
visual outcome
Gujarati
logMAR
repeatability
validity
visual acuity
Multiple sclerosis
optic neuritis
optical coherence tomography
retinal nerve fi ber layer
visual functions
Axon diameter
electron microscopy
nerve fiber layer
oligodendrocytes
pathology
Frequency doubling technology perimetry
pediatric visual field testing
standard automated perimetry
Central corneal thickness
glaucoma
pachymetry
20G Silicone rod
monocanalicular stent
canalicular laceration repair
Coat′s like response
pigmented paravenous chorioretinal atrophy
Retinochoroiditis radiata
Dacryocystectomy
oculosporidiosis
Rhinosporidium
Infectious scleritis
microbial scleritis
ocular infection
scleritis
Congenital ectropion
congenital eyelid imbrication syndrome
congenital floppy eyelid syndrome
congenital lax upper eyelid syndrome
down syndrome
Inner retinal layer thickness
optic nerve hypoplasia
outer retinal layer thickness
retinal nerve fiber layer thickness
spectral domain optical coherence tomography
Abducens nerve palsy
hyperhomocysteinemia
isolated abducens nerve palsy
nontraumatic
Inverted internal limiting membrane flap technique
macular hole
macular hole surgery
Ocular
positron emission tomography
tuberculosis
title Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
title_full Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
title_fullStr Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
title_full_unstemmed Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
title_short Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
title_sort clinical utility of 18 fluorodeoxyglucose fdg pet ct scans in patients with suspect ocular tuberculosis
topic Posterior open globe injuries
posterior to rectus insertion
zone III open globe injuries
Glaucoma severity
juvenile glaucoma
juvenile-onset primary open angle glaucoma
visual field defects
Diabetic retinopathy
renal transplant
visual outcome
Gujarati
logMAR
repeatability
validity
visual acuity
Multiple sclerosis
optic neuritis
optical coherence tomography
retinal nerve fi ber layer
visual functions
Axon diameter
electron microscopy
nerve fiber layer
oligodendrocytes
pathology
Frequency doubling technology perimetry
pediatric visual field testing
standard automated perimetry
Central corneal thickness
glaucoma
pachymetry
20G Silicone rod
monocanalicular stent
canalicular laceration repair
Coat′s like response
pigmented paravenous chorioretinal atrophy
Retinochoroiditis radiata
Dacryocystectomy
oculosporidiosis
Rhinosporidium
Infectious scleritis
microbial scleritis
ocular infection
scleritis
Congenital ectropion
congenital eyelid imbrication syndrome
congenital floppy eyelid syndrome
congenital lax upper eyelid syndrome
down syndrome
Inner retinal layer thickness
optic nerve hypoplasia
outer retinal layer thickness
retinal nerve fiber layer thickness
spectral domain optical coherence tomography
Abducens nerve palsy
hyperhomocysteinemia
isolated abducens nerve palsy
nontraumatic
Inverted internal limiting membrane flap technique
macular hole
macular hole surgery
Ocular
positron emission tomography
tuberculosis
url http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=Mehta
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