Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis
Systemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Indian Journal of Ophthalmology |
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Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=Mehta |
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author | Salil Mehta |
author_facet | Salil Mehta |
author_sort | Salil Mehta |
collection | DOAJ |
description | Systemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case 1: A 38-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active supraclavicular and chest lymph nodes. An aspiration cytology of the cervical lymph node revealed caseating granulomas suggestive of tuberculosis. Case 2: A 58-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active lymph nodes in the neck. A biopsy of the cervical lymph node revealed epithelioid granulomas suggestive of tuberculosis. Both patients were started on standard antitubercular therapy with a subsequent marked reduction of activity. PET/CT scans may suggest the sites of safe high-yield biopsies. |
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issn | 0301-4738 1998-3689 |
language | English |
last_indexed | 2024-12-11T01:10:35Z |
publishDate | 2013-01-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | Indian Journal of Ophthalmology |
spelling | doaj.art-2de986753b354309855d6704c77776a12022-12-22T01:26:02ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-01611060360510.4103/0301-4738.121091Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosisSalil MehtaSystemic imaging of patients with suspect ocular tuberculosis include chest X-rays and computed tomography (CT) scans. Reports have suggested a role for 18 fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) scans. We report on the clinical utility of 18 FDG PET/CT in two patients. Case 1: A 38-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active supraclavicular and chest lymph nodes. An aspiration cytology of the cervical lymph node revealed caseating granulomas suggestive of tuberculosis. Case 2: A 58-year-old female patient presented with recurrent anterior uveitis. A 18 FDG-PET scan revealed metabolically active lymph nodes in the neck. A biopsy of the cervical lymph node revealed epithelioid granulomas suggestive of tuberculosis. Both patients were started on standard antitubercular therapy with a subsequent marked reduction of activity. PET/CT scans may suggest the sites of safe high-yield biopsies.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=MehtaPosterior open globe injuriesposterior to rectus insertionzone III open globe injuriesGlaucoma severityjuvenile glaucomajuvenile-onset primary open angle glaucomavisual field defectsDiabetic retinopathyrenal transplantvisual outcomeGujaratilogMARrepeatabilityvalidityvisual acuityMultiple sclerosisoptic neuritisoptical coherence tomographyretinal nerve fi ber layervisual functionsAxon diameterelectron microscopynerve fiber layeroligodendrocytespathologyFrequency doubling technology perimetrypediatric visual field testingstandard automated perimetryCentral corneal thicknessglaucomapachymetry20G Silicone rodmonocanalicular stentcanalicular laceration repairCoat′s like responsepigmented paravenous chorioretinal atrophyRetinochoroiditis radiataDacryocystectomyoculosporidiosisRhinosporidiumInfectious scleritismicrobial scleritisocular infectionscleritisCongenital ectropioncongenital eyelid imbrication syndromecongenital floppy eyelid syndromecongenital lax upper eyelid syndromedown syndromeInner retinal layer thicknessoptic nerve hypoplasiaouter retinal layer thicknessretinal nerve fiber layer thicknessspectral domain optical coherence tomographyAbducens nerve palsyhyperhomocysteinemiaisolated abducens nerve palsynontraumaticInverted internal limiting membrane flap techniquemacular holemacular hole surgeryOcularpositron emission tomographytuberculosis |
spellingShingle | Salil Mehta Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis Indian Journal of Ophthalmology Posterior open globe injuries posterior to rectus insertion zone III open globe injuries Glaucoma severity juvenile glaucoma juvenile-onset primary open angle glaucoma visual field defects Diabetic retinopathy renal transplant visual outcome Gujarati logMAR repeatability validity visual acuity Multiple sclerosis optic neuritis optical coherence tomography retinal nerve fi ber layer visual functions Axon diameter electron microscopy nerve fiber layer oligodendrocytes pathology Frequency doubling technology perimetry pediatric visual field testing standard automated perimetry Central corneal thickness glaucoma pachymetry 20G Silicone rod monocanalicular stent canalicular laceration repair Coat′s like response pigmented paravenous chorioretinal atrophy Retinochoroiditis radiata Dacryocystectomy oculosporidiosis Rhinosporidium Infectious scleritis microbial scleritis ocular infection scleritis Congenital ectropion congenital eyelid imbrication syndrome congenital floppy eyelid syndrome congenital lax upper eyelid syndrome down syndrome Inner retinal layer thickness optic nerve hypoplasia outer retinal layer thickness retinal nerve fiber layer thickness spectral domain optical coherence tomography Abducens nerve palsy hyperhomocysteinemia isolated abducens nerve palsy nontraumatic Inverted internal limiting membrane flap technique macular hole macular hole surgery Ocular positron emission tomography tuberculosis |
title | Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis |
title_full | Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis |
title_fullStr | Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis |
title_full_unstemmed | Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis |
title_short | Clinical utility of 18 Fluorodeoxyglucose (FDG)-PET/CT scans in patients with suspect ocular tuberculosis |
title_sort | clinical utility of 18 fluorodeoxyglucose fdg pet ct scans in patients with suspect ocular tuberculosis |
topic | Posterior open globe injuries posterior to rectus insertion zone III open globe injuries Glaucoma severity juvenile glaucoma juvenile-onset primary open angle glaucoma visual field defects Diabetic retinopathy renal transplant visual outcome Gujarati logMAR repeatability validity visual acuity Multiple sclerosis optic neuritis optical coherence tomography retinal nerve fi ber layer visual functions Axon diameter electron microscopy nerve fiber layer oligodendrocytes pathology Frequency doubling technology perimetry pediatric visual field testing standard automated perimetry Central corneal thickness glaucoma pachymetry 20G Silicone rod monocanalicular stent canalicular laceration repair Coat′s like response pigmented paravenous chorioretinal atrophy Retinochoroiditis radiata Dacryocystectomy oculosporidiosis Rhinosporidium Infectious scleritis microbial scleritis ocular infection scleritis Congenital ectropion congenital eyelid imbrication syndrome congenital floppy eyelid syndrome congenital lax upper eyelid syndrome down syndrome Inner retinal layer thickness optic nerve hypoplasia outer retinal layer thickness retinal nerve fiber layer thickness spectral domain optical coherence tomography Abducens nerve palsy hyperhomocysteinemia isolated abducens nerve palsy nontraumatic Inverted internal limiting membrane flap technique macular hole macular hole surgery Ocular positron emission tomography tuberculosis |
url | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=10;spage=603;epage=605;aulast=Mehta |
work_keys_str_mv | AT salilmehta clinicalutilityof18fluorodeoxyglucosefdgpetctscansinpatientswithsuspectoculartuberculosis |