Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption
The monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanoacrylate (IANOPA) and monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanomethacrylate (IANOPMA) were synthesized by treating 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol with acryloylchloride/methacryloyl chloride. The above esterificat...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2024-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2024/6626223 |
| _version_ | 1827009789501112320 |
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| author | John Santhosh Kumar P. Kamaraj P. A. Vivekanand Govindasami Periyasami Mostafizur Rahaman Perumal Karthikeyan U. T. Uthappa Selvakumar Palaniappan |
| author_facet | John Santhosh Kumar P. Kamaraj P. A. Vivekanand Govindasami Periyasami Mostafizur Rahaman Perumal Karthikeyan U. T. Uthappa Selvakumar Palaniappan |
| author_sort | John Santhosh Kumar |
| collection | DOAJ |
| description | The monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanoacrylate (IANOPA) and monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanomethacrylate (IANOPMA) were synthesized by treating 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol with acryloylchloride/methacryloyl chloride. The above esterification reactions were carried out in the presence of triethylamine. By employing the free radical polymerization method, the synthesized monomers were converted into polymers by using an initiator 2, 2′-azobisisobutyronitrile in the presence of nitrogen environment at 70±2°C. The monomers and polymers were characterized by various techniques such as FT-IR, UV, 1H NMR, and 13C NMR spectroscopic analyses. Further, differential scanning calorimetry (DSC) was used to estimate the glass transition temperature (Tg). Gel permeation chromatography (GPC) was used to estimate the molecular weight of the polymers. In addition, monomer and polymer surfaces’ morphology was analyzed using SEM analysis. As a primary application, the effectiveness of synthesized monomers and polymers was explored as antibacterial agents against gram-positive bacteria (Staphylococcus aureus) and gram-negative bacteria (Pseudomonas aeruginosa) which were measured from their inhibitory zone diameters. Further, the synthesized polymers, poly-IANOPA and poly-IANOPMA, were utilized for the uptake ability study of heavy metal ions such as Zn2+, Cu2+, Ni2+, and Pb2+ present in water sources by equilibrium method. |
| first_indexed | 2024-03-08T05:35:40Z |
| format | Article |
| id | doaj.art-2deb626def1543eb98bf3177f9c97fb1 |
| institution | Directory Open Access Journal |
| issn | 1687-9430 |
| language | English |
| last_indexed | 2025-02-18T12:54:34Z |
| publishDate | 2024-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj.art-2deb626def1543eb98bf3177f9c97fb12024-11-02T03:57:45ZengHindawi LimitedInternational Journal of Polymer Science1687-94302024-01-01202410.1155/2024/6626223Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion AbsorptionJohn Santhosh Kumar0P. Kamaraj1P. A. Vivekanand2Govindasami Periyasami3Mostafizur Rahaman4Perumal Karthikeyan5U. T. Uthappa6Selvakumar Palaniappan7Department of ChemistryDepartment of ChemistryCentre for Catalysis ResearchDepartment of ChemistryDepartment of ChemistryDepartment of Chemistry and BiochemistrySchool of Chemical EngineeringDepartment of Food Science and Postharvest TechnologyThe monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanoacrylate (IANOPA) and monomer 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanomethacrylate (IANOPMA) were synthesized by treating 1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol with acryloylchloride/methacryloyl chloride. The above esterification reactions were carried out in the presence of triethylamine. By employing the free radical polymerization method, the synthesized monomers were converted into polymers by using an initiator 2, 2′-azobisisobutyronitrile in the presence of nitrogen environment at 70±2°C. The monomers and polymers were characterized by various techniques such as FT-IR, UV, 1H NMR, and 13C NMR spectroscopic analyses. Further, differential scanning calorimetry (DSC) was used to estimate the glass transition temperature (Tg). Gel permeation chromatography (GPC) was used to estimate the molecular weight of the polymers. In addition, monomer and polymer surfaces’ morphology was analyzed using SEM analysis. As a primary application, the effectiveness of synthesized monomers and polymers was explored as antibacterial agents against gram-positive bacteria (Staphylococcus aureus) and gram-negative bacteria (Pseudomonas aeruginosa) which were measured from their inhibitory zone diameters. Further, the synthesized polymers, poly-IANOPA and poly-IANOPMA, were utilized for the uptake ability study of heavy metal ions such as Zn2+, Cu2+, Ni2+, and Pb2+ present in water sources by equilibrium method.http://dx.doi.org/10.1155/2024/6626223 |
| spellingShingle | John Santhosh Kumar P. Kamaraj P. A. Vivekanand Govindasami Periyasami Mostafizur Rahaman Perumal Karthikeyan U. T. Uthappa Selvakumar Palaniappan Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption International Journal of Polymer Science |
| title | Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption |
| title_full | Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption |
| title_fullStr | Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption |
| title_full_unstemmed | Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption |
| title_short | Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption |
| title_sort | design of novel poly propranolol acrylate and methacrylate polymers through radical polymerization for antibacterial activity and metal ion absorption |
| url | http://dx.doi.org/10.1155/2024/6626223 |
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