Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets

Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate mechanisms underlying I/R injury hinders the development of effective therapeutic interventions. The Wnt signaling...

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Bibliographic Details
Main Authors: Meng Zhang, Qian Liu, Hui Meng, Hongxia Duan, Xin Liu, Jian Wu, Fei Gao, Shijun Wang, Rubin Tan, Jinxiang Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01688-x