Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.
Bibliographic Details
| Main Authors: |
Sang H. Lee,
Seung Min Shin,
Peng Zhong,
Hyun-Taek Kim,
Dong-Il Kim,
June Myoung Kim,
Won Do Heo,
Dae-Won Kim,
Chang-Yeol Yeo,
Cheol-Hee Kim,
Qing-song Liu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-05858-2
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