Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes
Iron deficiency leads to ferropenic anemia in humans. This study aimed to encapsulate iron-rich ovine and bovine erythrocytes using tara gum and native potato starch as matrices. Solutions containing 20% erythrocytes and different proportions of encapsulants (5, 10, and 20%) were used, followed by s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/15/19/3985 |
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| author | Carlos A. Ligarda-Samanez Elibet Moscoso-Moscoso David Choque-Quispe Betsy S. Ramos-Pacheco José C. Arévalo-Quijano Germán De la Cruz Mary L. Huamán-Carrión Uriel R. Quispe-Quezada Edgar Gutiérrez-Gómez Domingo J. Cabel-Moscoso Mauricio Muñoz-Melgarejo Wilber César Calsina Ponce |
| author_facet | Carlos A. Ligarda-Samanez Elibet Moscoso-Moscoso David Choque-Quispe Betsy S. Ramos-Pacheco José C. Arévalo-Quijano Germán De la Cruz Mary L. Huamán-Carrión Uriel R. Quispe-Quezada Edgar Gutiérrez-Gómez Domingo J. Cabel-Moscoso Mauricio Muñoz-Melgarejo Wilber César Calsina Ponce |
| author_sort | Carlos A. Ligarda-Samanez |
| collection | DOAJ |
| description | Iron deficiency leads to ferropenic anemia in humans. This study aimed to encapsulate iron-rich ovine and bovine erythrocytes using tara gum and native potato starch as matrices. Solutions containing 20% erythrocytes and different proportions of encapsulants (5, 10, and 20%) were used, followed by spray drying at 120 and 140 °C. Iron content in erythrocytes ranged between 2.24 and 2.52 mg of Fe/g; microcapsules ranged from 1.54 to 2.02 mg of Fe/g. Yields varied from 50.55 to 63.40%, and temperature and encapsulant proportion affected moisture and water activity. Various red hues, sizes, and shapes were observed in the microcapsules. SEM-EDS analysis revealed the surface presence of iron in microcapsules with openings on their exterior, along with a negative zeta potential. Thermal and infrared analyses confirmed core encapsulation within the matrices. Iron release varied between 92.30 and 93.13% at 120 min. Finally, the most effective treatments were those with higher encapsulant percentages and dried at elevated temperatures, which could enable their utilization in functional food fortification to combat anemia in developing countries. |
| first_indexed | 2024-03-10T21:36:31Z |
| format | Article |
| id | doaj.art-2df4deec0bfb4dd3970f65aa4e1ce7f4 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T21:36:31Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-2df4deec0bfb4dd3970f65aa4e1ce7f42023-11-19T14:57:17ZengMDPI AGPolymers2073-43602023-10-011519398510.3390/polym15193985Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine ErythrocytesCarlos A. Ligarda-Samanez0Elibet Moscoso-Moscoso1David Choque-Quispe2Betsy S. Ramos-Pacheco3José C. Arévalo-Quijano4Germán De la Cruz5Mary L. Huamán-Carrión6Uriel R. Quispe-Quezada7Edgar Gutiérrez-Gómez8Domingo J. Cabel-Moscoso9Mauricio Muñoz-Melgarejo10Wilber César Calsina Ponce11Nutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruNutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruNutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruNutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruDepartment of Education and Humanities, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruAgricultural Science Faculty, Universidad Nacional de San Cristobal de Huamanga, Ayacucho 05000, PeruNutraceuticals and Biomaterials Research Group, Universidad Nacional José María Arguedas, Andahuaylas 03701, PeruAgricultural and Forestry Business Engineering, Universidad Nacional Autónoma de Huanta, Ayacucho 05000, PeruEngineering and Management Faculty, Universidad Nacional Autónoma de Huanta, Ayacucho 05000, PeruAmbiental Engineering, Universidad Nacional San Luis Gonzaga, Ica 11001, PeruHuman Medicine Faculty, Universidad Peruana los Andes, Huancayo 12006, PeruSocial Sciences Faculty, Universidad Nacional del Altiplano, Puno 21001, PeruIron deficiency leads to ferropenic anemia in humans. This study aimed to encapsulate iron-rich ovine and bovine erythrocytes using tara gum and native potato starch as matrices. Solutions containing 20% erythrocytes and different proportions of encapsulants (5, 10, and 20%) were used, followed by spray drying at 120 and 140 °C. Iron content in erythrocytes ranged between 2.24 and 2.52 mg of Fe/g; microcapsules ranged from 1.54 to 2.02 mg of Fe/g. Yields varied from 50.55 to 63.40%, and temperature and encapsulant proportion affected moisture and water activity. Various red hues, sizes, and shapes were observed in the microcapsules. SEM-EDS analysis revealed the surface presence of iron in microcapsules with openings on their exterior, along with a negative zeta potential. Thermal and infrared analyses confirmed core encapsulation within the matrices. Iron release varied between 92.30 and 93.13% at 120 min. Finally, the most effective treatments were those with higher encapsulant percentages and dried at elevated temperatures, which could enable their utilization in functional food fortification to combat anemia in developing countries.https://www.mdpi.com/2073-4360/15/19/3985native potato starchtara gummicroencapsulationerythrocytesiron releasedspray drying |
| spellingShingle | Carlos A. Ligarda-Samanez Elibet Moscoso-Moscoso David Choque-Quispe Betsy S. Ramos-Pacheco José C. Arévalo-Quijano Germán De la Cruz Mary L. Huamán-Carrión Uriel R. Quispe-Quezada Edgar Gutiérrez-Gómez Domingo J. Cabel-Moscoso Mauricio Muñoz-Melgarejo Wilber César Calsina Ponce Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes Polymers native potato starch tara gum microencapsulation erythrocytes iron released spray drying |
| title | Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes |
| title_full | Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes |
| title_fullStr | Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes |
| title_full_unstemmed | Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes |
| title_short | Native Potato Starch and Tara Gum as Polymeric Matrices to Obtain Iron-Loaded Microcapsules from Ovine and Bovine Erythrocytes |
| title_sort | native potato starch and tara gum as polymeric matrices to obtain iron loaded microcapsules from ovine and bovine erythrocytes |
| topic | native potato starch tara gum microencapsulation erythrocytes iron released spray drying |
| url | https://www.mdpi.com/2073-4360/15/19/3985 |
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