The blockade of the renin-angiotensin system reverses tacrolimus related cardiovascular toxicity at the histopathological level

The blockade of the renin-angiotensin system reverses tacrolimus related cardiovascular toxicity at the histopathological level

Introduction. In this study, we investigate the toxic effects of tacrolimus (FK506) on the cardiovascular system at the histopathological level in a rat model and whether these effects can be reversed by the blockade of the renin-angiotensin system (RAS) by either an angiotensin-converting enzyme in...

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Bibliographic Details
Main Authors: Mehmet Agirbasli, Nurdan Papila-Topal, Betul Ogutmen, Hicran Deniz, Fulya Cakalagaoglu, Serhan Tuglular, Emel Akoglu
Format: Article
Language:English
Published: SAGE Publications 2007-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2007.009

Internet

https://doi.org/10.3317/jraas.2007.009

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