The blockade of the renin-angiotensin system reverses tacrolimus related cardiovascular toxicity at the histopathological level
Introduction. In this study, we investigate the toxic effects of tacrolimus (FK506) on the cardiovascular system at the histopathological level in a rat model and whether these effects can be reversed by the blockade of the renin-angiotensin system (RAS) by either an angiotensin-converting enzyme in...
Main Authors: | Mehmet Agirbasli, Nurdan Papila-Topal, Betul Ogutmen, Hicran Deniz, Fulya Cakalagaoglu, Serhan Tuglular, Emel Akoglu |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2007-06-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2007.009 |
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