Catalase Mediates the Inhibitory Actions of PPARδ against Angiotensin II-Triggered Hypertrophy in H9c2 Cardiomyocytes

Catalase Mediates the Inhibitory Actions of PPARδ against Angiotensin II-Triggered Hypertrophy in H9c2 Cardiomyocytes

Hypertrophy of myocytes has been implicated in cardiac dysfunctions affecting wall stress and patterns of gene expression. However, molecular targets potentially preventing cardiac hypertrophy have not been fully elucidated. In the present study, we demonstrate that upregulation of catalase by perox...

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Bibliographic Details
Main Authors: Jung Seok Hwang, Jinwoo Hur, Won Jin Lee, Jun Pil Won, Hyuk Gyoon Lee, Dae-Seog Lim, Eunsu Kim, Han Geuk Seo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antioxidants
Subjects:
angiotensin II
catalase
hypertrophy
peroxisome proliferator-activated receptor δ
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/10/8/1223

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