PNPLA1-Mediated Acylceramide Biosynthesis and Autosomal Recessive Congenital Ichthyosis

PNPLA1-Mediated Acylceramide Biosynthesis and Autosomal Recessive Congenital Ichthyosis

The stratum corneum of the epidermis acts as a life-sustaining permeability barrier. Unique heterogeneous ceramides, especially ω-O-acylceramides, are key components for the formation of stable lamellar membrane structures in the stratum corneum and are essential for a vital epidermal permeability b...

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Bibliographic Details
Main Authors: Fansi Zeng, Wenzhen Qin, Feifei Huang, Pingan Chang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Metabolites
Subjects:
PNPLA1
acylceramide
skin barrier
ARCI
gene mutation
Online Access:https://www.mdpi.com/2218-1989/12/8/685

Internet

https://www.mdpi.com/2218-1989/12/8/685

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