Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials
Abstract Background Central post-stroke pain (CPSP) is an under-recognized complication of stroke although it can lead to deterioration in quality of life and impairment in activities of daily living. Its estimated prevalence varies between 18.6 and 49%. Objective To investigate the prevalence and p...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-12-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41983-018-0041-z |
| _version_ | 1818036717060358144 |
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| author | Ahmed Osama Ahmed Abo Hagar Saly Elkholy Mohamed Negm Reda Abd El-Razek Marwa Orabi |
| author_facet | Ahmed Osama Ahmed Abo Hagar Saly Elkholy Mohamed Negm Reda Abd El-Razek Marwa Orabi |
| author_sort | Ahmed Osama |
| collection | DOAJ |
| description | Abstract Background Central post-stroke pain (CPSP) is an under-recognized complication of stroke although it can lead to deterioration in quality of life and impairment in activities of daily living. Its estimated prevalence varies between 18.6 and 49%. Objective To investigate the prevalence and predictors of CPSP in ischemic stroke patients and to find its relationship with somatosensory evoked potentials (SSEPs) and magnetic resonance imaging. Patients and methods Sixty five consecutive patients with recent first attack of ischemic stroke who were admitted to the Neurology Department, Suez Canal University Hospitals were recruited. Patients were subjected to clinical assessment, Hamilton depression rating scale, brain MRI, short-form McGill Pain Questionnaire (SF-MPQ), daily pain rating scale (DPRS), stimulus evoked pain, and SSEPs. Results The total prevalence rate of CPSP was 35.4% (n = 23). The mean age of the patients developed CPSP was significantly lower than those without CPSP (p = 0.004). Deep sensory dysfunction was statistically significantly higher among CPSP group than non-CPSP group (p = 0.001). CPSP group showed statistically significant higher prevalence of thalamic stroke (p = 0.007), as well as significant abnormalities in inter-peak interval (IPL) of median and tibial nerves SSEPs (p < 0.05). Thalamic group showed higher abnormalities in IPL of median and tibial nerves compared to extra-thalamic group, but without statistically differences. Conclusion The prevalence of CPSP was found to be 35.4%. Predictors of CPSP include; deep sensory dysfunction, prolongation of tibial N21–P40 IPL, smoking history, age < 50 years, presence of thalamic stroke and prolongation of median N9–N20 IPL. |
| first_indexed | 2024-12-10T07:15:23Z |
| format | Article |
| id | doaj.art-2e058176dcfc4123abbb6dde1779cf71 |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-12-10T07:15:23Z |
| publishDate | 2018-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-2e058176dcfc4123abbb6dde1779cf712022-12-22T01:57:56ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292018-12-015411710.1186/s41983-018-0041-zCentral post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentialsAhmed Osama0Ahmed Abo Hagar1Saly Elkholy2Mohamed Negm3Reda Abd El-Razek4Marwa Orabi5Neurology, Faculty of Medicine, Suez Canal UniversityNeurology, Faculty of Medicine, Suez Canal UniversityClinical Neurophysiology, Cairo UniversityNeurology, Faculty of Medicine, Suez Canal UniversityNeurology, Faculty of Medicine, Suez Canal UniversityNeurology, Faculty of Medicine, Suez Canal UniversityAbstract Background Central post-stroke pain (CPSP) is an under-recognized complication of stroke although it can lead to deterioration in quality of life and impairment in activities of daily living. Its estimated prevalence varies between 18.6 and 49%. Objective To investigate the prevalence and predictors of CPSP in ischemic stroke patients and to find its relationship with somatosensory evoked potentials (SSEPs) and magnetic resonance imaging. Patients and methods Sixty five consecutive patients with recent first attack of ischemic stroke who were admitted to the Neurology Department, Suez Canal University Hospitals were recruited. Patients were subjected to clinical assessment, Hamilton depression rating scale, brain MRI, short-form McGill Pain Questionnaire (SF-MPQ), daily pain rating scale (DPRS), stimulus evoked pain, and SSEPs. Results The total prevalence rate of CPSP was 35.4% (n = 23). The mean age of the patients developed CPSP was significantly lower than those without CPSP (p = 0.004). Deep sensory dysfunction was statistically significantly higher among CPSP group than non-CPSP group (p = 0.001). CPSP group showed statistically significant higher prevalence of thalamic stroke (p = 0.007), as well as significant abnormalities in inter-peak interval (IPL) of median and tibial nerves SSEPs (p < 0.05). Thalamic group showed higher abnormalities in IPL of median and tibial nerves compared to extra-thalamic group, but without statistically differences. Conclusion The prevalence of CPSP was found to be 35.4%. Predictors of CPSP include; deep sensory dysfunction, prolongation of tibial N21–P40 IPL, smoking history, age < 50 years, presence of thalamic stroke and prolongation of median N9–N20 IPL.http://link.springer.com/article/10.1186/s41983-018-0041-zStrokeCentral post-stroke painShort latency somatosensory evoked potentials |
| spellingShingle | Ahmed Osama Ahmed Abo Hagar Saly Elkholy Mohamed Negm Reda Abd El-Razek Marwa Orabi Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Stroke Central post-stroke pain Short latency somatosensory evoked potentials |
| title | Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| title_full | Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| title_fullStr | Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| title_full_unstemmed | Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| title_short | Central post-stroke pain: predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| title_sort | central post stroke pain predictors and relationship with magnetic resonance imaging and somatosensory evoked potentials |
| topic | Stroke Central post-stroke pain Short latency somatosensory evoked potentials |
| url | http://link.springer.com/article/10.1186/s41983-018-0041-z |
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