Acute human lethal poisoning with hexaflumuron: A case report
Background: Hexaflumuron is a benzoyl urea pesticide widely used in agriculture. This is the first case of severe toxicity of hexaflumuron. Case presentation: A 51-year-old man was admitted to the poisoning ward of the Emam-Reza Hospital for loss of consciousness and hypotension secondary to pestici...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2021-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-2244-en.html |
| _version_ | 1818930599285489664 |
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| author | Maryam Sayyari Dougabadi Leila Etemad Mohammad Moshiri |
| author_facet | Maryam Sayyari Dougabadi Leila Etemad Mohammad Moshiri |
| author_sort | Maryam Sayyari Dougabadi |
| collection | DOAJ |
| description | Background: Hexaflumuron is a benzoyl urea pesticide widely used in agriculture. This is the first case of severe toxicity of hexaflumuron.
Case presentation: A 51-year-old man was admitted to the poisoning ward of the Emam-Reza Hospital for loss of consciousness and hypotension secondary to pesticide toxicity. He had metabolic acidosis, bradycardia, and diffuse erythematous skin color change in the abdomen and legs. The results of toxicology tests were negative except positive test result for tricyclic antidepressants in immunochromatographic assay of urine. He was treated with normal saline, norepinephrine infusion and bicarbonate. His intoxication finally resulted to cardiac arrest and death on the 4th day of hospitalization, secondary to septic shock.
Conclusion: Acute poisoning with hexaflumuron can be life-threatening, thought its LD50 is greater than 5000 mg/kg. It may change the patient’s skin color to cherry and cause hypotension, loss of consciousness and metabolic acidosis, however, conclusive evidence to support these assumptions are required. |
| first_indexed | 2024-12-20T04:03:15Z |
| format | Article |
| id | doaj.art-2e0649ca5c4c439cbaba58b99629103b |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-12-20T04:03:15Z |
| publishDate | 2021-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-2e0649ca5c4c439cbaba58b99629103b2022-12-21T19:54:06ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722021-01-01121119123Acute human lethal poisoning with hexaflumuron: A case reportMaryam Sayyari Dougabadi0Leila Etemad1Mohammad Moshiri2 Deparment of emergency medicine, faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Department of Clinical Toxicology and Poisoning, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Background: Hexaflumuron is a benzoyl urea pesticide widely used in agriculture. This is the first case of severe toxicity of hexaflumuron. Case presentation: A 51-year-old man was admitted to the poisoning ward of the Emam-Reza Hospital for loss of consciousness and hypotension secondary to pesticide toxicity. He had metabolic acidosis, bradycardia, and diffuse erythematous skin color change in the abdomen and legs. The results of toxicology tests were negative except positive test result for tricyclic antidepressants in immunochromatographic assay of urine. He was treated with normal saline, norepinephrine infusion and bicarbonate. His intoxication finally resulted to cardiac arrest and death on the 4th day of hospitalization, secondary to septic shock. Conclusion: Acute poisoning with hexaflumuron can be life-threatening, thought its LD50 is greater than 5000 mg/kg. It may change the patient’s skin color to cherry and cause hypotension, loss of consciousness and metabolic acidosis, however, conclusive evidence to support these assumptions are required.http://caspjim.com/article-1-2244-en.htmlacute poisoninghexaflumuronpesticide |
| spellingShingle | Maryam Sayyari Dougabadi Leila Etemad Mohammad Moshiri Acute human lethal poisoning with hexaflumuron: A case report Caspian Journal of Internal Medicine acute poisoning hexaflumuron pesticide |
| title | Acute human lethal poisoning with hexaflumuron: A case report |
| title_full | Acute human lethal poisoning with hexaflumuron: A case report |
| title_fullStr | Acute human lethal poisoning with hexaflumuron: A case report |
| title_full_unstemmed | Acute human lethal poisoning with hexaflumuron: A case report |
| title_short | Acute human lethal poisoning with hexaflumuron: A case report |
| title_sort | acute human lethal poisoning with hexaflumuron a case report |
| topic | acute poisoning hexaflumuron pesticide |
| url | http://caspjim.com/article-1-2244-en.html |
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