Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, ma...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2021-10-01
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| Series: | ADMET and DMPK |
| Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/1137 |
| _version_ | 1818978433006305280 |
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| author | Matthias Fellner |
| author_facet | Matthias Fellner |
| author_sort | Matthias Fellner |
| collection | DOAJ |
| description | There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.
©2021 by the authors. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
| first_indexed | 2024-12-20T16:43:33Z |
| format | Article |
| id | doaj.art-2e0a5ce98495426a82046fdfad9f5dc0 |
| institution | Directory Open Access Journal |
| issn | 1848-7718 |
| language | English |
| last_indexed | 2024-12-20T16:43:33Z |
| publishDate | 2021-10-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | ADMET and DMPK |
| spelling | doaj.art-2e0a5ce98495426a82046fdfad9f5dc02022-12-21T19:32:58ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182021-10-0110.5599/admet.1137Newly discovered Staphylococcus aureus serine hydrolase probe and drug targetsMatthias Fellner0University of Otago, Dunedin, New ZealandThere is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. ©2021 by the authors. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).http://pub.iapchem.org/ojs/index.php/admet/article/view/1137 |
| spellingShingle | Matthias Fellner Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets ADMET and DMPK |
| title | Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets |
| title_full | Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets |
| title_fullStr | Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets |
| title_full_unstemmed | Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets |
| title_short | Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets |
| title_sort | newly discovered staphylococcus aureus serine hydrolase probe and drug targets |
| url | http://pub.iapchem.org/ojs/index.php/admet/article/view/1137 |
| work_keys_str_mv | AT matthiasfellner newlydiscoveredstaphylococcusaureusserinehydrolaseprobeanddrugtargets |