Evaluation of clinical outcomes in patients treated with heparin or direct thrombin inhibitors during extracorporeal membrane oxygenation: a systematic review and meta-analysis

Evaluation of clinical outcomes in patients treated with heparin or direct thrombin inhibitors during extracorporeal membrane oxygenation: a systematic review and meta-analysis

Abstract Background The number of patients treated with extracorporeal membrane oxygenation (ECMO) devices is increasing. Anticoagulation therapy is crucial to prevent thrombosis during ECMO therapy. Predominantly, heparin has been used as primary anticoagulant but direct thrombin inhibitors (DTI) h...

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Bibliographic Details
Main Authors: René M’Pembele, Sebastian Roth, Aljoscha Metzger, Anthony Nucaro, Alexandra Stroda, Amin Polzin, Markus W. Hollmann, Giovanna Lurati Buse, Ragnar Huhn
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Thrombosis Journal
Subjects:
Bivalirudin
Argatroban
Anticoagulation
Bleeding
Thrombosis
Mechanical circulatory support
Online Access:https://doi.org/10.1186/s12959-022-00401-2

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