The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis
Abstract Background Spinal manipulative therapy (SMT) is a guideline-recommended treatment option for spinal pain. The recommendation is based on multiple systematic reviews. However, these reviews fail to consider that clinical effects may depend on SMT “application procedures” (i.e., how and where...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-05-01
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| Series: | Chiropractic & Manual Therapies |
| Online Access: | https://doi.org/10.1186/s12998-023-00487-z |
| _version_ | 1797817827484237824 |
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| author | Casper G. Nim Sasha L. Aspinall Chad E. Cook Leticia A. Corrêa Megan Donaldson Aron S. Downie Steen Harsted Jan Hartvigsen Hazel J. Jenkins David McNaughton Luana Nyirö Stephen M. Perle Eric J. Roseen James J. Young Anika Young Gong-He Zhao Carsten B. Juhl |
| author_facet | Casper G. Nim Sasha L. Aspinall Chad E. Cook Leticia A. Corrêa Megan Donaldson Aron S. Downie Steen Harsted Jan Hartvigsen Hazel J. Jenkins David McNaughton Luana Nyirö Stephen M. Perle Eric J. Roseen James J. Young Anika Young Gong-He Zhao Carsten B. Juhl |
| author_sort | Casper G. Nim |
| collection | DOAJ |
| description | Abstract Background Spinal manipulative therapy (SMT) is a guideline-recommended treatment option for spinal pain. The recommendation is based on multiple systematic reviews. However, these reviews fail to consider that clinical effects may depend on SMT “application procedures” (i.e., how and where SMT is applied). Using network meta-analyses, we aim to investigate which SMT “application procedures” have the greatest magnitude of clinical effectiveness for reducing pain and disability, for any spinal complaint, at short-term and long-term follow-up. We will compare application procedural parameters by classifying the thrust application technique and the application site (patient positioning, assisted, vertebral target, region target, Technique name, forces, and vectors, application site selection approach and rationale) against: 1. Waiting list/no treatment; 2. Sham interventions not resembling SMT (e.g., detuned ultrasound); 3. Sham interventions resembling SMT; 4. Other therapies not recommended in clinical practice guidelines; and 5. Other therapies recommended in clinical practice guidelines. Secondly, we will examine how contextual elements, including procedural fidelity (whether the SMT was delivered as planned) and clinical applicability (whether the SMT is similar to clinical practice) of the SMT. Methods We will include randomized controlled trials (RCT) found through three search strategies, (i) exploratory, (ii) systematic, and (iii) other known sources. We define SMT as a high-velocity low-amplitude thrust or grade V mobilization. Eligibility is any RCT assessing SMT against any other type of SMT, any other active or sham intervention, or no treatment control on adult patients with pain in any spinal region. The RCTs must report on continuous pain intensity and/or disability outcomes. Two authors will independently review title and abstract screening, full-text screening, and data extraction. Spinal manipulative therapy techniques will be classified according to the technique application and choice of application sites. We will conduct a network-meta analysis using a frequentist approach and multiple subgroup and sensitivity analyses. Discussion This will be the most extensive review of thrust SMT to date, and will allow us to estimate the importance of different SMT application procedures used in clinical practice and taught across educational settings. Thus, the results are applicable to clinical practice, educational settings, and research studies. PROSPERO registration: CRD42022375836. |
| first_indexed | 2024-03-13T08:59:10Z |
| format | Article |
| id | doaj.art-2e0af5d5f23f4aca9d82935745bd4f7a |
| institution | Directory Open Access Journal |
| issn | 2045-709X |
| language | English |
| last_indexed | 2024-03-13T08:59:10Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Chiropractic & Manual Therapies |
| spelling | doaj.art-2e0af5d5f23f4aca9d82935745bd4f7a2023-05-28T11:23:07ZengBMCChiropractic & Manual Therapies2045-709X2023-05-013111910.1186/s12998-023-00487-zThe effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysisCasper G. Nim0Sasha L. Aspinall1Chad E. Cook2Leticia A. Corrêa3Megan Donaldson4Aron S. Downie5Steen Harsted6Jan Hartvigsen7Hazel J. Jenkins8David McNaughton9Luana Nyirö10Stephen M. Perle11Eric J. Roseen12James J. Young13Anika Young14Gong-He Zhao15Carsten B. Juhl16Medical Research Unit, Spine Centre of Southern Denmark, Lillebaelt Hospital, University Hospital of Southern DenmarkSchool of Allied Health, College of Health and Education, Murdoch UniversityDepartment of Orthopaedics, Duke UniversityDepartment of Chiropractic, Macquarie UniversityDepartment of Rehabilitation Sciences, Medical University of South CarolinaDepartment of Chiropractic, Macquarie UniversityMedical Research Unit, Spine Centre of Southern Denmark, Lillebaelt Hospital, University Hospital of Southern DenmarkDepartment of Sports Science and Clinical Biomechanics, Center for Muscle and Joint Health, University of Southern DenmarkDepartment of Chiropractic, Macquarie UniversitySchool of Psychological Sciences, Macquarie UniversityDepartment of Chiropractic Medicine, Balgrist University Hospital, University of ZurichSchool of Allied Health, College of Health and Education, Murdoch UniversitySection of General Internal Medicine, Department of Medicine, Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston UniversityDepartment of Sports Science and Clinical Biomechanics, Center for Muscle and Joint Health, University of Southern DenmarkDepartment of Chiropractic, Macquarie UniversityDepartment of Sports Science and Clinical Biomechanics, Center for Muscle and Joint Health, University of Southern DenmarkDepartment of Sports Science and Clinical Biomechanics, Center for Muscle and Joint Health, University of Southern DenmarkAbstract Background Spinal manipulative therapy (SMT) is a guideline-recommended treatment option for spinal pain. The recommendation is based on multiple systematic reviews. However, these reviews fail to consider that clinical effects may depend on SMT “application procedures” (i.e., how and where SMT is applied). Using network meta-analyses, we aim to investigate which SMT “application procedures” have the greatest magnitude of clinical effectiveness for reducing pain and disability, for any spinal complaint, at short-term and long-term follow-up. We will compare application procedural parameters by classifying the thrust application technique and the application site (patient positioning, assisted, vertebral target, region target, Technique name, forces, and vectors, application site selection approach and rationale) against: 1. Waiting list/no treatment; 2. Sham interventions not resembling SMT (e.g., detuned ultrasound); 3. Sham interventions resembling SMT; 4. Other therapies not recommended in clinical practice guidelines; and 5. Other therapies recommended in clinical practice guidelines. Secondly, we will examine how contextual elements, including procedural fidelity (whether the SMT was delivered as planned) and clinical applicability (whether the SMT is similar to clinical practice) of the SMT. Methods We will include randomized controlled trials (RCT) found through three search strategies, (i) exploratory, (ii) systematic, and (iii) other known sources. We define SMT as a high-velocity low-amplitude thrust or grade V mobilization. Eligibility is any RCT assessing SMT against any other type of SMT, any other active or sham intervention, or no treatment control on adult patients with pain in any spinal region. The RCTs must report on continuous pain intensity and/or disability outcomes. Two authors will independently review title and abstract screening, full-text screening, and data extraction. Spinal manipulative therapy techniques will be classified according to the technique application and choice of application sites. We will conduct a network-meta analysis using a frequentist approach and multiple subgroup and sensitivity analyses. Discussion This will be the most extensive review of thrust SMT to date, and will allow us to estimate the importance of different SMT application procedures used in clinical practice and taught across educational settings. Thus, the results are applicable to clinical practice, educational settings, and research studies. PROSPERO registration: CRD42022375836.https://doi.org/10.1186/s12998-023-00487-z |
| spellingShingle | Casper G. Nim Sasha L. Aspinall Chad E. Cook Leticia A. Corrêa Megan Donaldson Aron S. Downie Steen Harsted Jan Hartvigsen Hazel J. Jenkins David McNaughton Luana Nyirö Stephen M. Perle Eric J. Roseen James J. Young Anika Young Gong-He Zhao Carsten B. Juhl The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis Chiropractic & Manual Therapies |
| title | The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis |
| title_full | The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis |
| title_fullStr | The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis |
| title_full_unstemmed | The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis |
| title_short | The effectiveness of spinal manipulative therapy procedures for spine pain: protocol for a systematic review and network meta-analysis |
| title_sort | effectiveness of spinal manipulative therapy procedures for spine pain protocol for a systematic review and network meta analysis |
| url | https://doi.org/10.1186/s12998-023-00487-z |
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