Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome

Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome

Extracellular vesicles (EVs) are secreted from many tumors, including glioblastoma multiforme (GBM), the most common and lethal brain tumor in adults, which shows high resistance to current therapies and poor patient prognosis. Given the high relevance of the information provided by cancer cell secr...

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Bibliographic Details
Main Authors: Fabrizio Di Giuseppe, Lucia Ricci-Vitiani, Roberto Pallini, Roberta Di Pietro, Patrizia Di Iorio, Giuliano Ascani, Renata Ciccarelli, Stefania Angelucci
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
glioblastoma-derived stem-like cells (GSCs)
microvesicles
exosomes
proteomic analysis
P2X7 receptors
Online Access:https://www.mdpi.com/2073-4409/13/7/571

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