The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study

Abstract Background The use of potentially inappropriate medications (PIMs) are associated with negative health effects for older adults. The purpose of this study was to apply national register data to investigate the impact of hospitalisation to geriatric wards in Norway on the use of medications...

Full description

Bibliographic Details
Main Authors: Jeanette Schultz Johansen, Kjell H. Halvorsen, Kristian Svendsen, Kjerstin Havnes, Beate H. Garcia
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Geriatrics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12877-020-01585-w
_version_ 1818305595793473536
author Jeanette Schultz Johansen
Kjell H. Halvorsen
Kristian Svendsen
Kjerstin Havnes
Beate H. Garcia
author_facet Jeanette Schultz Johansen
Kjell H. Halvorsen
Kristian Svendsen
Kjerstin Havnes
Beate H. Garcia
author_sort Jeanette Schultz Johansen
collection DOAJ
description Abstract Background The use of potentially inappropriate medications (PIMs) are associated with negative health effects for older adults. The purpose of this study was to apply national register data to investigate the impact of hospitalisation to geriatric wards in Norway on the use of medications and PIMs, and to compare two explicit PIM identification tools. Methods We included 715 patients ≥65 years (mean 82.5, SD = 7.8) admitted to Norwegian geriatric wards in 2013 identified from The Norwegian Patient Registry, and collected their medication use from the Norwegian Prescription Database. Medication use before and after hospitalisation was compared and screened for PIMs applying a subset of the European Union (EU)(7)-PIM list and the Norwegian General Practice – Nursing Home (NORGEP-NH) list part A and B. Results The mean number of medications increased from 6.5 (SD = 3.5) before to 7.5 (SD = 3.5) (CI:1.2–0.8, p < 0.001) after hospitalisation. The proportion of patients with PIMs increased from before to after hospitalisation according to the EU(7)-PIM list (from 62.4 to 69.2%, p < 0.001), but not according to The NORGEP-NH list (from 49.9 to 50.6%, p = 0.73). The EU(7)-PIM list and the NORGEP-NH list had more than 70% agreement on the classification of patients as PIM users. Conclusions Medication use increased after hospitalisation to geriatric wards. We did not find that geriatric hospital care leads to a general improvement in PIM use after hospitalisation. According to a subset of the EU(7)-PIM list, PIM use increased after hospitalisation. This increase was not identified by the NORGEP-NH list part A and B. It is feasible to use health register data to investigate the impact of hospitalisation to geriatric wards on medication use and PIMs.
first_indexed 2024-12-13T06:29:06Z
format Article
id doaj.art-2e0c443a60704028a1c887ee2991e0ed
institution Directory Open Access Journal
issn 1471-2318
language English
last_indexed 2024-12-13T06:29:06Z
publishDate 2020-06-01
publisher BMC
record_format Article
series BMC Geriatrics
spelling doaj.art-2e0c443a60704028a1c887ee2991e0ed2022-12-21T23:56:39ZengBMCBMC Geriatrics1471-23182020-06-012011910.1186/s12877-020-01585-wThe impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register studyJeanette Schultz Johansen0Kjell H. Halvorsen1Kristian Svendsen2Kjerstin Havnes3Beate H. Garcia4Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of NorwayAbstract Background The use of potentially inappropriate medications (PIMs) are associated with negative health effects for older adults. The purpose of this study was to apply national register data to investigate the impact of hospitalisation to geriatric wards in Norway on the use of medications and PIMs, and to compare two explicit PIM identification tools. Methods We included 715 patients ≥65 years (mean 82.5, SD = 7.8) admitted to Norwegian geriatric wards in 2013 identified from The Norwegian Patient Registry, and collected their medication use from the Norwegian Prescription Database. Medication use before and after hospitalisation was compared and screened for PIMs applying a subset of the European Union (EU)(7)-PIM list and the Norwegian General Practice – Nursing Home (NORGEP-NH) list part A and B. Results The mean number of medications increased from 6.5 (SD = 3.5) before to 7.5 (SD = 3.5) (CI:1.2–0.8, p < 0.001) after hospitalisation. The proportion of patients with PIMs increased from before to after hospitalisation according to the EU(7)-PIM list (from 62.4 to 69.2%, p < 0.001), but not according to The NORGEP-NH list (from 49.9 to 50.6%, p = 0.73). The EU(7)-PIM list and the NORGEP-NH list had more than 70% agreement on the classification of patients as PIM users. Conclusions Medication use increased after hospitalisation to geriatric wards. We did not find that geriatric hospital care leads to a general improvement in PIM use after hospitalisation. According to a subset of the EU(7)-PIM list, PIM use increased after hospitalisation. This increase was not identified by the NORGEP-NH list part A and B. It is feasible to use health register data to investigate the impact of hospitalisation to geriatric wards on medication use and PIMs.http://link.springer.com/article/10.1186/s12877-020-01585-wPotentially inappropriate medicationsHealth register dataDrug therapyEU(7)-PIM listNORGEP-NH listHospitalization
spellingShingle Jeanette Schultz Johansen
Kjell H. Halvorsen
Kristian Svendsen
Kjerstin Havnes
Beate H. Garcia
The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
BMC Geriatrics
Potentially inappropriate medications
Health register data
Drug therapy
EU(7)-PIM list
NORGEP-NH list
Hospitalization
title The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
title_full The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
title_fullStr The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
title_full_unstemmed The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
title_short The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study
title_sort impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications a health register study
topic Potentially inappropriate medications
Health register data
Drug therapy
EU(7)-PIM list
NORGEP-NH list
Hospitalization
url http://link.springer.com/article/10.1186/s12877-020-01585-w
work_keys_str_mv AT jeanetteschultzjohansen theimpactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kjellhhalvorsen theimpactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kristiansvendsen theimpactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kjerstinhavnes theimpactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT beatehgarcia theimpactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT jeanetteschultzjohansen impactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kjellhhalvorsen impactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kristiansvendsen impactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT kjerstinhavnes impactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy
AT beatehgarcia impactofhospitalisationtogeriatricwardsontheuseofmedicationsandpotentiallyinappropriatemedicationsahealthregisterstudy