Label-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells
Abstract Label-free image analysis has several advantages with respect to the development of drug screening platforms. However, the evaluation of drug-responsive cells based exclusively on morphological information is challenging, especially in cases of morphologically heterogeneous cells or a small...
Main Authors: | Yuta Imai, Madoka Iida, Kei Kanie, Masahisa Katsuno, Ryuji Kato |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-12250-0 |
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