Label-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells

Abstract Label-free image analysis has several advantages with respect to the development of drug screening platforms. However, the evaluation of drug-responsive cells based exclusively on morphological information is challenging, especially in cases of morphologically heterogeneous cells or a small...

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Bibliographic Details
Main Authors: Yuta Imai, Madoka Iida, Kei Kanie, Masahisa Katsuno, Ryuji Kato
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12250-0

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