The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy.
Immunotherapy has revolutionised cancer treatment. However, not all cancer patients benefit, and current stratification strategies based primarily on PD1 status and mutation burden are far from perfect. We hypothesised that high activation of an innate response relative to the adaptive response may...
Main Authors: | Johanne Ahrenfeldt, Ditte S Christensen, Andreas B Østergaard, Judit Kisistók, Mateo Sokač, Nicolai J Birkbak |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0281375 |
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