Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department
Background: This study was conducted to evaluate the incidence of medication discrepancies and its related factors using medication reconciliation method in patients admitted to the emergency department of Tehran University of Medical Sciences hospitals. Methods: In this cross-sectional study, 200...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-07-01
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| Series: | Iranian Journal of Public Health |
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| Online Access: | https://ijph.tums.ac.ir/index.php/ijph/article/view/10608 |
| _version_ | 1818772290984214528 |
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| author | Morvarid ZARIF-YEGANEH Mansoor RASTEGARPANAH Gholamreza GARMAROUDI Molouk HADJIBABAIE Hojjat SHEIKH MOTAHAR VAHEDI |
| author_facet | Morvarid ZARIF-YEGANEH Mansoor RASTEGARPANAH Gholamreza GARMAROUDI Molouk HADJIBABAIE Hojjat SHEIKH MOTAHAR VAHEDI |
| author_sort | Morvarid ZARIF-YEGANEH |
| collection | DOAJ |
| description | Background: This study was conducted to evaluate the incidence of medication discrepancies and its related factors using medication reconciliation method in patients admitted to the emergency department of Tehran University of Medical Sciences hospitals.
Methods: In this cross-sectional study, 200 adult patients with at least one chronic disease that used two regular prescription medications were included in 2015. After 24 h of admission, demographic data and patient's home medications were collected. Medication discrepancies were assessed through comparison of a best possible medication history list with the physician's orders.
Results: Out of 200 patients (mean age, 61.5 yr; 86 males, 114 women), 77.5% of patients had one or more medication discrepancies. The most common discrepancies were medication omission (35.49%), change (14.22%) and substitution (10.97%), respectively. The relationship between number of comorbid conditions (P=0.025), regular home medications (P=<0.001), high-risk medications (P=0.032), medications pharmacological classes (P=<0.001) and medication discrepancies were statistically significant. Cardiovascular drugs compared to other medications classes showed the highest discrepancies (36.2%). Multiple logistic regression showed that the drug groups, including anti-infective for systemic use (OR=8.43; 95%CI 2.5-28.2; P=0.001), Antineoplastic and Immuno-modulator Agents (OR=0.49; 95%CI 0.27-0.87; P=0.016), Blood and Blood-Forming Organs (OR=0.33; 95%CI 0.21-0.52; P<0.001), Muscular-Skeletal System (OR=2.4; 95%CI 1.13-5.1; P=0.022), Nervous-System (OR=2.75; 95%CI 1.7-4.4; P<0.001), Respiratory-System (OR=0.38; 95%CI 0.22-0.67; P=0.001) were associated with the drug discrepancy.
Conclusion: A medication discrepancy occurs commonly at hospital emergency department. Understanding the type and frequency of discrepancies with using structured medication reconciliation process can help clinicians to prevent them. |
| first_indexed | 2024-12-18T10:07:01Z |
| format | Article |
| id | doaj.art-2e10d096322c4eb3b1d0126e9da41f2f |
| institution | Directory Open Access Journal |
| issn | 2251-6085 2251-6093 |
| language | English |
| last_indexed | 2024-12-18T10:07:01Z |
| publishDate | 2017-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-2e10d096322c4eb3b1d0126e9da41f2f2022-12-21T21:11:32ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932017-07-01468Incidence of Medication Discrepancies and its Predicting Factors in Emergency DepartmentMorvarid ZARIF-YEGANEH0Mansoor RASTEGARPANAH1Gholamreza GARMAROUDI2Molouk HADJIBABAIE3Hojjat SHEIKH MOTAHAR VAHEDI4Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranDept. of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranDept. of Health Promotion and Education, School of Public Health, Tehran University of Medical Sciences, Tehran, IranResearch Center for Rational Use of Drugs and Clinical Pharmacy Dept., Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranEmergency Dept., Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranBackground: This study was conducted to evaluate the incidence of medication discrepancies and its related factors using medication reconciliation method in patients admitted to the emergency department of Tehran University of Medical Sciences hospitals. Methods: In this cross-sectional study, 200 adult patients with at least one chronic disease that used two regular prescription medications were included in 2015. After 24 h of admission, demographic data and patient's home medications were collected. Medication discrepancies were assessed through comparison of a best possible medication history list with the physician's orders. Results: Out of 200 patients (mean age, 61.5 yr; 86 males, 114 women), 77.5% of patients had one or more medication discrepancies. The most common discrepancies were medication omission (35.49%), change (14.22%) and substitution (10.97%), respectively. The relationship between number of comorbid conditions (P=0.025), regular home medications (P=<0.001), high-risk medications (P=0.032), medications pharmacological classes (P=<0.001) and medication discrepancies were statistically significant. Cardiovascular drugs compared to other medications classes showed the highest discrepancies (36.2%). Multiple logistic regression showed that the drug groups, including anti-infective for systemic use (OR=8.43; 95%CI 2.5-28.2; P=0.001), Antineoplastic and Immuno-modulator Agents (OR=0.49; 95%CI 0.27-0.87; P=0.016), Blood and Blood-Forming Organs (OR=0.33; 95%CI 0.21-0.52; P<0.001), Muscular-Skeletal System (OR=2.4; 95%CI 1.13-5.1; P=0.022), Nervous-System (OR=2.75; 95%CI 1.7-4.4; P<0.001), Respiratory-System (OR=0.38; 95%CI 0.22-0.67; P=0.001) were associated with the drug discrepancy. Conclusion: A medication discrepancy occurs commonly at hospital emergency department. Understanding the type and frequency of discrepancies with using structured medication reconciliation process can help clinicians to prevent them.https://ijph.tums.ac.ir/index.php/ijph/article/view/10608Medication discrepanciesMedication reconciliationEmergency department |
| spellingShingle | Morvarid ZARIF-YEGANEH Mansoor RASTEGARPANAH Gholamreza GARMAROUDI Molouk HADJIBABAIE Hojjat SHEIKH MOTAHAR VAHEDI Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department Iranian Journal of Public Health Medication discrepancies Medication reconciliation Emergency department |
| title | Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department |
| title_full | Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department |
| title_fullStr | Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department |
| title_full_unstemmed | Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department |
| title_short | Incidence of Medication Discrepancies and its Predicting Factors in Emergency Department |
| title_sort | incidence of medication discrepancies and its predicting factors in emergency department |
| topic | Medication discrepancies Medication reconciliation Emergency department |
| url | https://ijph.tums.ac.ir/index.php/ijph/article/view/10608 |
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