Association of loneliness with all-cause mortality: A meta-analysis.

Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main character...

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Main Authors: Laura Alejandra Rico-Uribe, Francisco Félix Caballero, Natalia Martín-María, María Cabello, José Luis Ayuso-Mateos, Marta Miret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5754055?pdf=render
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author Laura Alejandra Rico-Uribe
Francisco Félix Caballero
Natalia Martín-María
María Cabello
José Luis Ayuso-Mateos
Marta Miret
author_facet Laura Alejandra Rico-Uribe
Francisco Félix Caballero
Natalia Martín-María
María Cabello
José Luis Ayuso-Mateos
Marta Miret
author_sort Laura Alejandra Rico-Uribe
collection DOAJ
description Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression.
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spelling doaj.art-2e10e04658b5497cad4397593ab79d462022-12-21T17:58:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01131e019003310.1371/journal.pone.0190033Association of loneliness with all-cause mortality: A meta-analysis.Laura Alejandra Rico-UribeFrancisco Félix CaballeroNatalia Martín-MaríaMaría CabelloJosé Luis Ayuso-MateosMarta MiretLoneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression.http://europepmc.org/articles/PMC5754055?pdf=render
spellingShingle Laura Alejandra Rico-Uribe
Francisco Félix Caballero
Natalia Martín-María
María Cabello
José Luis Ayuso-Mateos
Marta Miret
Association of loneliness with all-cause mortality: A meta-analysis.
PLoS ONE
title Association of loneliness with all-cause mortality: A meta-analysis.
title_full Association of loneliness with all-cause mortality: A meta-analysis.
title_fullStr Association of loneliness with all-cause mortality: A meta-analysis.
title_full_unstemmed Association of loneliness with all-cause mortality: A meta-analysis.
title_short Association of loneliness with all-cause mortality: A meta-analysis.
title_sort association of loneliness with all cause mortality a meta analysis
url http://europepmc.org/articles/PMC5754055?pdf=render
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