Safety and Toxicology Study of Hu7691, a Novel AKT Inhibitor, following Oral Administration in Rats

Safety and Toxicology Study of Hu7691, a Novel AKT Inhibitor, following Oral Administration in Rats

Hu7691 represents a novel Pan-Akt kinase inhibitor, demonstrating excellent selectivity towards non-AGC kinase families and pronounced inhibitory effects on the proliferation of multiple tumor cell lines. However, there is currently a notable absence of in vivo toxicological research evidence concer...

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Bibliographic Details
Main Authors: Renhua Gai, Chao Chen, Wei Zhang, Jian Ma, Xiaomeng Wang, Xiaoqing Chi, Guangxing Li
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Toxics
Subjects:
Hu7691
14-day exposure
oral toxicity study
SD rats
formulation
histopathology
Online Access:https://www.mdpi.com/2305-6304/11/11/880

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