Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis

Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis

Introduction: Lung adenocarcinoma is the most common type of lung cancer and typically carries a high number of mutations. However, the genetic background of the tumors varies according to patients’ ethnic background and smoking status. Little data is available on the mutational landscape and the fr...

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Bibliographic Details
Main Authors: Eva-Maria Talvitie, Lassi Liljeroos, Heikki Vilhonen, Katri Orte, Ilmo Leivo, Markku Kallajoki, Pekka Taimen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Lung adenocarcinoma
Mutational landscape
Never-smoker
SMARCA4
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622000598

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