RNA Structural Requirements for Nucleocapsid Protein-Mediated Extended Dimer Formation

Retroviruses package two copies of their genomic RNA (gRNA) as non-covalently linked dimers. Many studies suggest that the retroviral nucleocapsid protein (NC) plays an important role in gRNA dimerization. The upper part of the L3 RNA stem-loop in the 5′ leader of the avian leukosis virus (ALV) is c...

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Bibliographic Details
Main Authors: Françoise Chaminade, Jean-Luc Darlix, Philippe Fossé
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/3/606