The Effects of Retinoic Acid on the Expression of HNF4α and Cdx-2 Genes in Caco-2 Cells as a Model of Intestinal Barrier
Background and Aim: Retinoic acid (RA) is involved in protecting the intestinal barrier, inducing differentiation, growth and proliferation of epithelial cells. There are several hypotheses about the mechanism of induction of apoptosis by RA, but few studies have been performed on the role of HNF4α...
Main Authors: | Mahshad Karambeigi, Hadi Cheraghi, Arash Alizadeh |
---|---|
Format: | Article |
Language: | fas |
Published: |
Kurdistan University of Medical Sciences
2023-10-01
|
Series: | مجله علمی دانشگاه علوم پزشکی کردستان |
Subjects: | |
Online Access: | http://sjku.muk.ac.ir/article-1-7360-en.pdf |
Similar Items
-
Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (<i>RARβ</i>) Gene in Hepatocytes
by: Reza Zolfaghari, et al.
Published: (2023-05-01) -
Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine
by: Kiranmayi Vemuri, et al.
Published: (2023-08-01) -
Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver
by: Aamir Salam Teeli, et al.
Published: (2021-10-01) -
Immunoexpression of CDX2 in metastatic nonintestinal adenocarcinomas: an immunohistochemical pitfall and its pathological implications
by: Krachi Agarwal, et al.
Published: (2023-03-01) -
Loss of SATB2 Occurs More Frequently Than CDX2 Loss in Colorectal Carcinoma and Identifies Particularly Aggressive Cancers in High-Risk Subgroups
by: Maxime Schmitt, et al.
Published: (2021-12-01)