Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience
Wojciech Tański,1 Adrianna Szalonka,2 Beata Tomasiewicz1 1Department of Internal Medicine, 4th Military Teaching Hospital, Wroclaw, Poland; 2Centre for Research and Innovation, 4th Military Teaching Hospital, Wroclaw, PolandCorrespondence: Wojciech Tański, Department of Interna...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-03-01
|
| Series: | Psychology Research and Behavior Management |
| Subjects: | |
| Online Access: | https://www.dovepress.com/quality-of-life-and-depression-in-rheumatoid-arthritis-patients-treate-peer-reviewed-fulltext-article-PRBM |
| _version_ | 1818492292790484992 |
|---|---|
| author | Tański W Szalonka A Tomasiewicz B |
| author_facet | Tański W Szalonka A Tomasiewicz B |
| author_sort | Tański W |
| collection | DOAJ |
| description | Wojciech Tański,1 Adrianna Szalonka,2 Beata Tomasiewicz1 1Department of Internal Medicine, 4th Military Teaching Hospital, Wroclaw, Poland; 2Centre for Research and Innovation, 4th Military Teaching Hospital, Wroclaw, PolandCorrespondence: Wojciech Tański, Department of Internal Medicine, 4th Military Teaching Hospital, Weigla 5, Wroclaw, 50-981, Poland, Email dr.wojciech.tanski@gmail.comIntroduction: Patients with rheumatoid arthritis (RA) often experience depression, which has a very negative impact on the assessment of the quality of life (QoL). However, there are not many studies that assess the relationship between depression and QoL in RA patients. The aim of the study was to assess the level of QoL and determine the mutual relationship between anxiety and depression levels and QoL in patients treated for RA.Material and Methods: The study included 101 patients (aged:52.4± 16.97), who met the established criteria for a diagnosis of RA and treatment with a biological agent. Only standardized tools were used to examine the patients: WHO-QoL, HADS and the VAS scale.Results: The mean RA duration in the group studied was 13.54± 9.51 years and the disease activity score was 4.8± 0.8. The mean QoL perception score was 3.48± 0.8. Nearly 40% of the respondents could not clearly determine their QoL, perceiving it as neither poor nor good, and 10% believed their QoL is poor or very poor. The correlation analysis revealed that anxiety is significantly and negatively associated with QoL in the psychological domain (r = − 0.472, p < 0.001) and social domain (r = − 0.298, p = 0.023) and depression is significantly and negatively associated with QoL in the psychological domain (r = − 0.322, p = 0.01) and physical health domain (r = − 0.209, p = 0.04). In the multiple linear regression model, depression was an independent negative predictor affecting the following domains: perception of QoL and perception of health, and physical health.Conclusion: RA patients treated with biologics present a low level of health perception and an average level of QoL perception. Depression and anxiety negatively correlate with QoL domains: the higher the anxiety and depression levels, the poorer the QoL in the psychological and social relationships domains. Depression is an independent determinant of decreased QoL.Keywords: rheumatoid arthritis, quality of life, depression, anxiety, predictors |
| first_indexed | 2024-12-10T17:41:07Z |
| format | Article |
| id | doaj.art-2e259e6d26fd4ac190e7f83fbf3326ff |
| institution | Directory Open Access Journal |
| issn | 1179-1578 |
| language | English |
| last_indexed | 2024-12-10T17:41:07Z |
| publishDate | 2022-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Psychology Research and Behavior Management |
| spelling | doaj.art-2e259e6d26fd4ac190e7f83fbf3326ff2022-12-22T01:39:22ZengDove Medical PressPsychology Research and Behavior Management1179-15782022-03-01Volume 1549150173385Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre ExperienceTański WSzalonka ATomasiewicz BWojciech Tański,1 Adrianna Szalonka,2 Beata Tomasiewicz1 1Department of Internal Medicine, 4th Military Teaching Hospital, Wroclaw, Poland; 2Centre for Research and Innovation, 4th Military Teaching Hospital, Wroclaw, PolandCorrespondence: Wojciech Tański, Department of Internal Medicine, 4th Military Teaching Hospital, Weigla 5, Wroclaw, 50-981, Poland, Email dr.wojciech.tanski@gmail.comIntroduction: Patients with rheumatoid arthritis (RA) often experience depression, which has a very negative impact on the assessment of the quality of life (QoL). However, there are not many studies that assess the relationship between depression and QoL in RA patients. The aim of the study was to assess the level of QoL and determine the mutual relationship between anxiety and depression levels and QoL in patients treated for RA.Material and Methods: The study included 101 patients (aged:52.4± 16.97), who met the established criteria for a diagnosis of RA and treatment with a biological agent. Only standardized tools were used to examine the patients: WHO-QoL, HADS and the VAS scale.Results: The mean RA duration in the group studied was 13.54± 9.51 years and the disease activity score was 4.8± 0.8. The mean QoL perception score was 3.48± 0.8. Nearly 40% of the respondents could not clearly determine their QoL, perceiving it as neither poor nor good, and 10% believed their QoL is poor or very poor. The correlation analysis revealed that anxiety is significantly and negatively associated with QoL in the psychological domain (r = − 0.472, p < 0.001) and social domain (r = − 0.298, p = 0.023) and depression is significantly and negatively associated with QoL in the psychological domain (r = − 0.322, p = 0.01) and physical health domain (r = − 0.209, p = 0.04). In the multiple linear regression model, depression was an independent negative predictor affecting the following domains: perception of QoL and perception of health, and physical health.Conclusion: RA patients treated with biologics present a low level of health perception and an average level of QoL perception. Depression and anxiety negatively correlate with QoL domains: the higher the anxiety and depression levels, the poorer the QoL in the psychological and social relationships domains. Depression is an independent determinant of decreased QoL.Keywords: rheumatoid arthritis, quality of life, depression, anxiety, predictorshttps://www.dovepress.com/quality-of-life-and-depression-in-rheumatoid-arthritis-patients-treate-peer-reviewed-fulltext-article-PRBMrheumatoid arthritisquality of lifedepressionanxietypredictors |
| spellingShingle | Tański W Szalonka A Tomasiewicz B Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience Psychology Research and Behavior Management rheumatoid arthritis quality of life depression anxiety predictors |
| title | Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience |
| title_full | Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience |
| title_fullStr | Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience |
| title_full_unstemmed | Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience |
| title_short | Quality of Life and Depression in Rheumatoid Arthritis Patients Treated with Biologics – A Single Centre Experience |
| title_sort | quality of life and depression in rheumatoid arthritis patients treated with biologics ndash a single centre experience |
| topic | rheumatoid arthritis quality of life depression anxiety predictors |
| url | https://www.dovepress.com/quality-of-life-and-depression-in-rheumatoid-arthritis-patients-treate-peer-reviewed-fulltext-article-PRBM |
| work_keys_str_mv | AT tanskiw qualityoflifeanddepressioninrheumatoidarthritispatientstreatedwithbiologicsndashasinglecentreexperience AT szalonkaa qualityoflifeanddepressioninrheumatoidarthritispatientstreatedwithbiologicsndashasinglecentreexperience AT tomasiewiczb qualityoflifeanddepressioninrheumatoidarthritispatientstreatedwithbiologicsndashasinglecentreexperience |