Do body composition parameters correlate with response to targeted therapy in ER+/HER2- metastatic breast cancer patients? Role of sarcopenia and obesity

Do body composition parameters correlate with response to targeted therapy in ER+/HER2- metastatic breast cancer patients? Role of sarcopenia and obesity

PurposeTo investigate the association between body composition parameters, sarcopenia, obesity and prognosis in patients with metastatic ER+/HER2- breast cancer under therapy with cyclin-dependent kinase (CDK) 4/6 inhibitors.Methods92 patients with biopsy-proven metastatic ER+/HER2- breast cancer, t...

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Bibliographic Details
Main Authors: Endi Kripa, Veronica Rizzo, Francesca Galati, Giuliana Moffa, Federica Cicciarelli, Carlo Catalano, Federica Pediconi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
body composition
sarcopenia
obesity
metastatic breast cancer
CDK 4/6 inhibitors
automatic segmentation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.987012/full

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