Antimicrobial peptides of human saliva

Among the many functions of human saliva, its digestive and protective properties have attracted the most interest. Human saliva contains a number of physical, physicochemical and chemical agents that protect oral tissues against by various microorganisms and their metabolic products. Among such pro...

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Main Authors: Dožić Ivan, Todorović Tatjana
Format: Article
Language:English
Published: Serbian Medical Society - Dental Section, Belgrade 2005-01-01
Series:Stomatološki glasnik Srbije
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0039-1743/2005/0039-17430504208D.pdf
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author Dožić Ivan
Todorović Tatjana
author_facet Dožić Ivan
Todorović Tatjana
author_sort Dožić Ivan
collection DOAJ
description Among the many functions of human saliva, its digestive and protective properties have attracted the most interest. Human saliva contains a number of physical, physicochemical and chemical agents that protect oral tissues against by various microorganisms and their metabolic products. Among such protective factors, the flushing effect of saliva flow is the most important one, not only because it so effectively removes exogenous and endogenous microorganisms and their products into the gut but also because a steady supply of saliva guarantees continuous presence of both non-immune and immune factors in the mouth. The most important antimicrobial peptides in saliva are: histatins, defensins, lactoferrin, cathelicidins, mucins, calprotectin, lysozyme, oral peroxidase. Antimicrobial peptides are components of complex host secretions, acting synergisticaly with other innate defence molecules to combat infection and control resident microbial populations throughout the oral cavity.
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spelling doaj.art-2e2c457f06054f32a782a0f46472b76f2022-12-21T23:35:09ZengSerbian Medical Society - Dental Section, BelgradeStomatološki glasnik Srbije0039-17432005-01-0152420821610.2298/SGS0504208DAntimicrobial peptides of human salivaDožić IvanTodorović TatjanaAmong the many functions of human saliva, its digestive and protective properties have attracted the most interest. Human saliva contains a number of physical, physicochemical and chemical agents that protect oral tissues against by various microorganisms and their metabolic products. Among such protective factors, the flushing effect of saliva flow is the most important one, not only because it so effectively removes exogenous and endogenous microorganisms and their products into the gut but also because a steady supply of saliva guarantees continuous presence of both non-immune and immune factors in the mouth. The most important antimicrobial peptides in saliva are: histatins, defensins, lactoferrin, cathelicidins, mucins, calprotectin, lysozyme, oral peroxidase. Antimicrobial peptides are components of complex host secretions, acting synergisticaly with other innate defence molecules to combat infection and control resident microbial populations throughout the oral cavity.http://www.doiserbia.nb.rs/img/doi/0039-1743/2005/0039-17430504208D.pdfsalivaantimicrobial peptidesinnate defences
spellingShingle Dožić Ivan
Todorović Tatjana
Antimicrobial peptides of human saliva
Stomatološki glasnik Srbije
saliva
antimicrobial peptides
innate defences
title Antimicrobial peptides of human saliva
title_full Antimicrobial peptides of human saliva
title_fullStr Antimicrobial peptides of human saliva
title_full_unstemmed Antimicrobial peptides of human saliva
title_short Antimicrobial peptides of human saliva
title_sort antimicrobial peptides of human saliva
topic saliva
antimicrobial peptides
innate defences
url http://www.doiserbia.nb.rs/img/doi/0039-1743/2005/0039-17430504208D.pdf
work_keys_str_mv AT dozicivan antimicrobialpeptidesofhumansaliva
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