Cationic BODIPY Photosensitizers for Mitochondrion-Targeted Fluorescence Cell-Imaging and Photodynamic Therapy

Cationic BODIPY Photosensitizers for Mitochondrion-Targeted Fluorescence Cell-Imaging and Photodynamic Therapy

The straightforward synthesis of three cationic boron-dipyrromethene (BODIPY) derivatives and their mitochondria-targeting and photodynamic therapeutic (PDT) capabilities are reported. Two cancer cell lines (HeLa and MCF-7) were used to investigate the PDT activity of the dyes. Compared to their non...

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Bibliographic Details
Main Authors: Isabel Wen Badon, Jun-Pil Jee, Temmy Pegarro Vales, Chanwoo Kim, Seungbin Lee, Jaesung Yang, Si Kyung Yang, Ho-Joong Kim
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
BODIPY
cationic
mitochondria
photodynamic therapy
photosensitizer
Online Access:https://www.mdpi.com/1999-4923/15/5/1512

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