IFNγ-primed periodontal ligament cells regulate T-cell responses via IFNγ-inducible mediators and ICAM-1-mediated direct cell contact

IFNγ-primed periodontal ligament cells regulate T-cell responses via IFNγ-inducible mediators and ICAM-1-mediated direct cell contact

Periodontal ligament (PDL) cells help maintain tissue homeostasis by balancing PDL tissue inflammation and regeneration. However, the mechanisms by which interferon γ (IFNγ) modulate this process are not yet fully understood. The present study aimed to examine the effect of primed and non-primed PDL...

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Bibliographic Details
Main Authors: Weerachai Singhatanadgit, Setthawut Kitpakornsanti, Montree Toso, Prasit Pavasant
Format: Article
Language:English
Published: The Royal Society 2022-07-01
Series:Royal Society Open Science
Subjects:
interferon γ
periodontal ligament cells
T lymphocytes
intercellular adhesion molecule-1
transforming growth factor β1
immunosuppression
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.220056

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