Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production

Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production

Abstract Background Plasmodium falciparum haemozoin, a detoxification product of digested haemoglobin from infected erythrocytes, is released into the bloodstream upon schizont rupture and accumulates in leukocytes. High levels of haemozoin correlate with disease severity. Some studies have shown th...

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Bibliographic Details
Main Authors: Yolanda Corbett, Sarah D’Alessandro, Silvia Parapini, Diletta Scaccabarozzi, Parisa Kalantari, Stefania Zava, Flavio Giavarini, Donatella Caruso, Irma Colombo, Timothy J. Egan, Nicoletta Basilico
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum haemozoin
Macrophages
l-Arginine
Inducible nitric oxide synthase
Nitric oxide
Online Access:http://link.springer.com/article/10.1186/s12936-018-2602-0

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