Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells?
Splenic B-cell marginal zone lymphoma (SMZL) – a rare B-cell non-Hodgkin, s lymphoma, which is represented morphologically by mature lymphoid cells, corresponding to lymphocytes of secondary follicles marginal zone by immunological characteristics. Plasma cell differentiation can be in marginal zone...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-12-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/165 |
| _version_ | 1797855526401343488 |
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| author | U. L. Julhakyan V. N. Dvirnyk L. P. Mendeleeva |
| author_facet | U. L. Julhakyan V. N. Dvirnyk L. P. Mendeleeva |
| author_sort | U. L. Julhakyan |
| collection | DOAJ |
| description | Splenic B-cell marginal zone lymphoma (SMZL) – a rare B-cell non-Hodgkin, s lymphoma, which is represented morphologically by mature lymphoid cells, corresponding to lymphocytes of secondary follicles marginal zone by immunological characteristics. Plasma cell differentiation can be in marginal zone lymphoma, but we described a single case of abundance of Mott cells as a tumor substrate in splenic B-cell marginal zone lymphoma.We present the first case of SMZL represented by Mott cells. This was the second case of Mott cells tumor described in Russia.This observation is the only case among the collected material of splenic lymphomas. The morphological pattern is characterized by marked proliferation of monoclonal lymphoid cells with plasma cell differentiation with presence of Mott cells and is evidence of intense intracellular secretion of immunoglobulins. |
| first_indexed | 2024-04-09T20:25:06Z |
| format | Article |
| id | doaj.art-2e36748853124e928ab8b9cb01609d13 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:25:06Z |
| publishDate | 2015-12-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-2e36748853124e928ab8b9cb01609d132023-03-30T20:15:11ZrusABV-pressОнкогематология1818-83462413-40232015-12-01104343710.17650/1818-8346-2015-10-4-34-37177Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells?U. L. Julhakyan0V. N. Dvirnyk1L. P. Mendeleeva2National Research Center for Hematology, Ministry of Health of RussiaNational Research Center for Hematology, Ministry of Health of RussiaNational Research Center for Hematology, Ministry of Health of RussiaSplenic B-cell marginal zone lymphoma (SMZL) – a rare B-cell non-Hodgkin, s lymphoma, which is represented morphologically by mature lymphoid cells, corresponding to lymphocytes of secondary follicles marginal zone by immunological characteristics. Plasma cell differentiation can be in marginal zone lymphoma, but we described a single case of abundance of Mott cells as a tumor substrate in splenic B-cell marginal zone lymphoma.We present the first case of SMZL represented by Mott cells. This was the second case of Mott cells tumor described in Russia.This observation is the only case among the collected material of splenic lymphomas. The morphological pattern is characterized by marked proliferation of monoclonal lymphoid cells with plasma cell differentiation with presence of Mott cells and is evidence of intense intracellular secretion of immunoglobulins.https://oncohematology.abvpress.ru/ongm/article/view/165splenic b-cell lymphomamott cellscytologyhistochemistryimmunoglobulinskappaimmunohistochemical study |
| spellingShingle | U. L. Julhakyan V. N. Dvirnyk L. P. Mendeleeva Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? Онкогематология splenic b-cell lymphoma mott cells cytology histochemistry immunoglobulins kappa immunohistochemical study |
| title | Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? |
| title_full | Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? |
| title_fullStr | Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? |
| title_full_unstemmed | Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? |
| title_short | Splenic B-cell marginal zone lymphoma with marked plasmocytic differentiation: tumor variant from Mott cells? |
| title_sort | splenic b cell marginal zone lymphoma with marked plasmocytic differentiation tumor variant from mott cells |
| topic | splenic b-cell lymphoma mott cells cytology histochemistry immunoglobulins kappa immunohistochemical study |
| url | https://oncohematology.abvpress.ru/ongm/article/view/165 |
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