Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis

Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis

Abstract Background Context: Methotrexate (MTX) is a cornerstone in the treatment of juvenile idiopathic arthritis (JIA). MTX treatment is commonly associated with nausea. Large inter-individual variation exists in the level of MTX-induced nausea, possibly due to genetic factors. Purpose: To investi...

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Bibliographic Details
Main Authors: Nini Kyvsgaard, Torben Stamm Mikkelsen, Thomas D. Als, Anne Estmann Christensen, Thomas J. Corydon, Troels Herlin
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Pediatric Rheumatology Online Journal
Subjects:
JIA
Juvenile idiopathic arthritis
SNPs
Single nucleotide polymorphisms
MTX
Methotrexate
Online Access:https://doi.org/10.1186/s12969-021-00539-9

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