Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy
Objective: Our aim was to investigate the effect of tamoxifen on cervical smear of patients with breast cancer at our clinic.Methods: The data of patients with breast cancer who had received tamoxifen were analyzed between 2006 and 2014, retrospectively. Pap smear results, age, gravidity, parity, sm...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2015-12-01
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| Series: | İstanbul Medical Journal |
| Subjects: | |
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http://imj.galenos.com.tr/archives/archive-detail/article-preview/pap-smear-results-of-women-with-breast-cancer-usin/20923
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| _version_ | 1797917036390645760 |
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| author | Gülsüm Uysal Sema Sezgin Göksu Dilek Ünal Fulya Çağlı Hatice Akkaya Hüseyin Aksoy Yusuf Madendağ Gökhan Açmaz |
| author_facet | Gülsüm Uysal Sema Sezgin Göksu Dilek Ünal Fulya Çağlı Hatice Akkaya Hüseyin Aksoy Yusuf Madendağ Gökhan Açmaz |
| author_sort | Gülsüm Uysal |
| collection | DOAJ |
| description | Objective: Our aim was to investigate the effect of tamoxifen on cervical smear of patients with breast cancer at our clinic.Methods: The data of patients with breast cancer who had received tamoxifen were analyzed between 2006 and 2014, retrospectively. Pap smear results, age, gravidity, parity, smoking status, age of first birth, and detailed gynecologic and obstetric history of patients were noted. Patients who had not received at least one-year tamoxifen therapy and patients without cervicovaginal smear controls or those who left or had received interrupted tamoxifen treatment were excluded. The pap smear results of the tamoxifen and control groups were analyzed.Results: A total of 246 patients (123 in the tamoxifen group and 123 in the control group) were included in this study. None of the patients had cervical squamous intraepithelial lesions and atypical glandular lesions. Atypical squamous cells were significantly higher in the tamoxifen group than in the control group (p=0.03).Conclusion:The use of tamoxifen may be associated with benign squamous atypia in cervical smears. Therefore, pelvic examination and pap smear test are recommended for breast cancer patients annually. |
| first_indexed | 2024-04-10T13:06:56Z |
| format | Article |
| id | doaj.art-2e3b46e78093479f8ede73ff5b6cb3fb |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T13:06:56Z |
| publishDate | 2015-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-2e3b46e78093479f8ede73ff5b6cb3fb2023-02-15T16:12:53ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2015-12-0116414915110.5152/imj.2015.6364413049054Pap Smear Results of Women with Breast Cancer Using Tamoxifen TherapyGülsüm Uysal0Sema Sezgin Göksu1Dilek Ünal2Fulya Çağlı3Hatice Akkaya4Hüseyin Aksoy5Yusuf Madendağ6Gökhan Açmaz7 Clinic of Gynecology and Obstetrics, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Medical Oncology, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Medical Oncology, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Gynecology and Obstetrics, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Gynecology and Obstetrics, Kayseri Training and Research Hospital, Kayseri, Türkiye Kayseri Military Hospital, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Gynecology and Obstetrics, Kayseri Training and Research Hospital, Kayseri, Türkiye Clinic of Gynecology and Obstetrics, Kayseri Training and Research Hospital, Kayseri, Türkiye Objective: Our aim was to investigate the effect of tamoxifen on cervical smear of patients with breast cancer at our clinic.Methods: The data of patients with breast cancer who had received tamoxifen were analyzed between 2006 and 2014, retrospectively. Pap smear results, age, gravidity, parity, smoking status, age of first birth, and detailed gynecologic and obstetric history of patients were noted. Patients who had not received at least one-year tamoxifen therapy and patients without cervicovaginal smear controls or those who left or had received interrupted tamoxifen treatment were excluded. The pap smear results of the tamoxifen and control groups were analyzed.Results: A total of 246 patients (123 in the tamoxifen group and 123 in the control group) were included in this study. None of the patients had cervical squamous intraepithelial lesions and atypical glandular lesions. Atypical squamous cells were significantly higher in the tamoxifen group than in the control group (p=0.03).Conclusion:The use of tamoxifen may be associated with benign squamous atypia in cervical smears. Therefore, pelvic examination and pap smear test are recommended for breast cancer patients annually. http://imj.galenos.com.tr/archives/archive-detail/article-preview/pap-smear-results-of-women-with-breast-cancer-usin/20923 Tamoxifencervical smearatypia |
| spellingShingle | Gülsüm Uysal Sema Sezgin Göksu Dilek Ünal Fulya Çağlı Hatice Akkaya Hüseyin Aksoy Yusuf Madendağ Gökhan Açmaz Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy İstanbul Medical Journal Tamoxifen cervical smear atypia |
| title | Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy |
| title_full | Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy |
| title_fullStr | Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy |
| title_full_unstemmed | Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy |
| title_short | Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy |
| title_sort | pap smear results of women with breast cancer using tamoxifen therapy |
| topic | Tamoxifen cervical smear atypia |
| url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/pap-smear-results-of-women-with-breast-cancer-usin/20923
|
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