Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications
The goal of personalized medicine is to target the right treatments to the right patients at the right time. Patients with a variety of cancers and other complex diseases are regularly tested as part of patient care, enabling physicians to personalize patient monitoring and treatment. Among the soug...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/11/9/2362 |
| _version_ | 1797517852551413760 |
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| author | Lucia Napione |
| author_facet | Lucia Napione |
| author_sort | Lucia Napione |
| collection | DOAJ |
| description | The goal of personalized medicine is to target the right treatments to the right patients at the right time. Patients with a variety of cancers and other complex diseases are regularly tested as part of patient care, enabling physicians to personalize patient monitoring and treatment. Among the sought-after diagnostic tools, there is an increasing interest and need for those based on a low-cost, easy, rapid, and accurate method for the detection of specific circulating biomarkers above a detection threshold. Lateral flow tests (LFTs), enhanced by nanotechnology, can fulfil these requirements, providing a significant support to personalized patient monitoring. In this review, after a short historical synopsis of membrane-based lateral flow assays, including a description of a typical configuration of a LFT strip, a careful collection is presented of the best characterized nanotechnology approaches previously reported for the enhancement of target detection performance. The attempt is to offer an overview of currently integrated nanotechnologies in LFTs, fostering the actual future development of advantageous diagnostic devices for patient monitoring. |
| first_indexed | 2024-03-10T07:21:58Z |
| format | Article |
| id | doaj.art-2e3d7da6f6c740fa8a1ea61025699e4c |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T07:21:58Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-2e3d7da6f6c740fa8a1ea61025699e4c2023-11-22T14:31:23ZengMDPI AGNanomaterials2079-49912021-09-01119236210.3390/nano11092362Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine ApplicationsLucia Napione0Department of Applied Science and Technology, Politecnico di Torino, 10129 Torino, ItalyThe goal of personalized medicine is to target the right treatments to the right patients at the right time. Patients with a variety of cancers and other complex diseases are regularly tested as part of patient care, enabling physicians to personalize patient monitoring and treatment. Among the sought-after diagnostic tools, there is an increasing interest and need for those based on a low-cost, easy, rapid, and accurate method for the detection of specific circulating biomarkers above a detection threshold. Lateral flow tests (LFTs), enhanced by nanotechnology, can fulfil these requirements, providing a significant support to personalized patient monitoring. In this review, after a short historical synopsis of membrane-based lateral flow assays, including a description of a typical configuration of a LFT strip, a careful collection is presented of the best characterized nanotechnology approaches previously reported for the enhancement of target detection performance. The attempt is to offer an overview of currently integrated nanotechnologies in LFTs, fostering the actual future development of advantageous diagnostic devices for patient monitoring.https://www.mdpi.com/2079-4991/11/9/2362circulating biomarkersnanotechnological toolsfunctionalized surfacedevice |
| spellingShingle | Lucia Napione Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications Nanomaterials circulating biomarkers nanotechnological tools functionalized surface device |
| title | Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications |
| title_full | Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications |
| title_fullStr | Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications |
| title_full_unstemmed | Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications |
| title_short | Integrated Nanomaterials and Nanotechnologies in Lateral Flow Tests for Personalized Medicine Applications |
| title_sort | integrated nanomaterials and nanotechnologies in lateral flow tests for personalized medicine applications |
| topic | circulating biomarkers nanotechnological tools functionalized surface device |
| url | https://www.mdpi.com/2079-4991/11/9/2362 |
| work_keys_str_mv | AT lucianapione integratednanomaterialsandnanotechnologiesinlateralflowtestsforpersonalizedmedicineapplications |