Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children

Introduction. A persistent trend towards a decrease in the incidence of extrapulmonary tuberculosis is noted both in the Omsk region and throughout the Russian FederationPurpose of the study. To study anamnestic, epidemiological and clinical features of children diagnosed with renal tuberculosis and...

Full description

Bibliographic Details
Main Authors: N. I. Porkulevich, A. V. Mordyk
Format: Article
Language:Russian
Published: Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education 2021-03-01
Series:Вестник урологии
Subjects:
Online Access:https://www.urovest.ru/jour/article/view/414
_version_ 1826565461512290304
author N. I. Porkulevich
A. V. Mordyk
author_facet N. I. Porkulevich
A. V. Mordyk
author_sort N. I. Porkulevich
collection DOAJ
description Introduction. A persistent trend towards a decrease in the incidence of extrapulmonary tuberculosis is noted both in the Omsk region and throughout the Russian FederationPurpose of the study. To study anamnestic, epidemiological and clinical features of children diagnosed with renal tuberculosis and other extrapulmonary localizations, established by typical clinical and radiological manifestations or proven bacteriologically or histologically.Materials and methods. A retrospective study data was carried out from 125 children aged 0-14 years in the period 2001-2018 with registered as «extrapulmonary tuberculosis» with or without lung involvement. Group 1 consisted of 50 patients with a typical clinical and radiological picture of tuberculosis, group 2 - 75 cases, with a specific extrapulmonary process, verified bacteriologically and/or using molecular genetic methods or histology. The differences between groups were determined using Pearson's χ2 test.Results. The predominance in the structure of confirmed and established extrapulmonary process of renal tuberculosis was established, and children living in urban areas had better accessibility of diagnostic methods for verifying extrapulmonary tuberculosis (62.7%, p < 0.05). A history of concomitant pathology (94.7%, p < 0.05) and the availability of the lesion for bacteriological or histological examination (urine, pus, punctate) increased the likelihood of diagnosis verification. Most of the considered factors for renal tuberculosis in children did not differ significantly. Hyperergic results (up to 24%, p < 0.05) of immunological tests, the presence of complaints of dysuric disorders (21%, p < 0.05) prevailing in groups of children with an established diagnosis of tuberculosis kidneys, only suggest the presence of MBT-infection and do not prove the specific nature of the disease, while systematic preventive work on the examination of the risk group allows timely diagnosis of the disease at an early stage of the disease (up to 26%, p < 0.05).Conclusion. The widespread improvement of material and technical equipment, the introduction of new diagnostic techniques (PCR of urine) into routine practice, training of medical personnel in assessing prevalence issues and early detection of the disease can improve the quality of verification of this nosology.
first_indexed 2024-03-07T14:24:02Z
format Article
id doaj.art-2e418e7b6f714d52a5debc72ab1a9302
institution Directory Open Access Journal
issn 2308-6424
language Russian
last_indexed 2025-03-14T10:36:07Z
publishDate 2021-03-01
publisher Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education
record_format Article
series Вестник урологии
spelling doaj.art-2e418e7b6f714d52a5debc72ab1a93022025-03-02T10:59:28ZrusMinistry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional EducationВестник урологии2308-64242021-03-0191566310.21886/2308-6424-2021-9-1-56-63291Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in childrenN. I. Porkulevich0A. V. Mordyk1Omsk State Medical University; Clinical Anti-tuberculosis DispensaryOmsk State Medical UniversityIntroduction. A persistent trend towards a decrease in the incidence of extrapulmonary tuberculosis is noted both in the Omsk region and throughout the Russian FederationPurpose of the study. To study anamnestic, epidemiological and clinical features of children diagnosed with renal tuberculosis and other extrapulmonary localizations, established by typical clinical and radiological manifestations or proven bacteriologically or histologically.Materials and methods. A retrospective study data was carried out from 125 children aged 0-14 years in the period 2001-2018 with registered as «extrapulmonary tuberculosis» with or without lung involvement. Group 1 consisted of 50 patients with a typical clinical and radiological picture of tuberculosis, group 2 - 75 cases, with a specific extrapulmonary process, verified bacteriologically and/or using molecular genetic methods or histology. The differences between groups were determined using Pearson's χ2 test.Results. The predominance in the structure of confirmed and established extrapulmonary process of renal tuberculosis was established, and children living in urban areas had better accessibility of diagnostic methods for verifying extrapulmonary tuberculosis (62.7%, p < 0.05). A history of concomitant pathology (94.7%, p < 0.05) and the availability of the lesion for bacteriological or histological examination (urine, pus, punctate) increased the likelihood of diagnosis verification. Most of the considered factors for renal tuberculosis in children did not differ significantly. Hyperergic results (up to 24%, p < 0.05) of immunological tests, the presence of complaints of dysuric disorders (21%, p < 0.05) prevailing in groups of children with an established diagnosis of tuberculosis kidneys, only suggest the presence of MBT-infection and do not prove the specific nature of the disease, while systematic preventive work on the examination of the risk group allows timely diagnosis of the disease at an early stage of the disease (up to 26%, p < 0.05).Conclusion. The widespread improvement of material and technical equipment, the introduction of new diagnostic techniques (PCR of urine) into routine practice, training of medical personnel in assessing prevalence issues and early detection of the disease can improve the quality of verification of this nosology.https://www.urovest.ru/jour/article/view/414tuberculosisextrapulmonary tuberculosisrenal tuberculosisgeneralized tuberculosisconfirmed diagnosischildren
spellingShingle N. I. Porkulevich
A. V. Mordyk
Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
Вестник урологии
tuberculosis
extrapulmonary tuberculosis
renal tuberculosis
generalized tuberculosis
confirmed diagnosis
children
title Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
title_full Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
title_fullStr Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
title_full_unstemmed Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
title_short Features of renal tuberculosis and other extrapulmonary tuberculosis localizations, depending on the presence or absence of the diagnosis confirmation in children
title_sort features of renal tuberculosis and other extrapulmonary tuberculosis localizations depending on the presence or absence of the diagnosis confirmation in children
topic tuberculosis
extrapulmonary tuberculosis
renal tuberculosis
generalized tuberculosis
confirmed diagnosis
children
url https://www.urovest.ru/jour/article/view/414
work_keys_str_mv AT niporkulevich featuresofrenaltuberculosisandotherextrapulmonarytuberculosislocalizationsdependingonthepresenceorabsenceofthediagnosisconfirmationinchildren
AT avmordyk featuresofrenaltuberculosisandotherextrapulmonarytuberculosislocalizationsdependingonthepresenceorabsenceofthediagnosisconfirmationinchildren