In the moonlight: non-catalytic functions of ubiquitin and ubiquitin-like proteases

In the moonlight: non-catalytic functions of ubiquitin and ubiquitin-like proteases

Proteases that cleave ubiquitin or ubiquitin-like proteins (UBLs) are critical players in maintaining the homeostasis of the organism. Concordantly, their dysregulation has been directly linked to various diseases, including cancer, neurodegeneration, developmental aberrations, cardiac disorders and...

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Bibliographic Details
Main Authors: Marta Campos Alonso, Klaus-Peter Knobeloch
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
deubiquitinase
ubiquitin-like protease
non-catalytic function
non-hydrolytic function
non-enzymatic function
protein moonlighting
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1349509/full

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