Recent Advances in Electrochemical Immunosensors
Immunosensors have experienced a very significant growth in recent years, driven by the need for fast, sensitive, portable and easy-to-use devices to detect biomarkers for clinical diagnosis or to monitor organic pollutants in natural or industrial environments. Advances in the field of signal ampli...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-04-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/17/4/794 |
| _version_ | 1811302421800943616 |
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| author | Benoît Piro Steeve Reisberg |
| author_facet | Benoît Piro Steeve Reisberg |
| author_sort | Benoît Piro |
| collection | DOAJ |
| description | Immunosensors have experienced a very significant growth in recent years, driven by the need for fast, sensitive, portable and easy-to-use devices to detect biomarkers for clinical diagnosis or to monitor organic pollutants in natural or industrial environments. Advances in the field of signal amplification using enzymatic reactions, nanomaterials such as carbon nanotubes, graphene and graphene derivatives, metallic nanoparticles (gold, silver, various oxides or metal complexes), or magnetic beads show how it is possible to improve collection, binding or transduction performances and reach the requirements for realistic clinical diagnostic or environmental control. This review presents these most recent advances; it focuses first on classical electrode substrates, then moves to carbon-based nanostructured ones including carbon nanotubes, graphene and other carbon materials, metal or metal-oxide nanoparticles, magnetic nanoparticles, dendrimers and, to finish, explore the use of ionic liquids. Analytical performances are systematically covered and compared, depending on the detection principle, but also from a chronological perspective, from 2012 to 2016 and early 2017. |
| first_indexed | 2024-04-13T07:27:37Z |
| format | Article |
| id | doaj.art-2e43239ae0454126bd9c0b296e13f380 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-13T07:27:37Z |
| publishDate | 2017-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-2e43239ae0454126bd9c0b296e13f3802022-12-22T02:56:26ZengMDPI AGSensors1424-82202017-04-0117479410.3390/s17040794s17040794Recent Advances in Electrochemical ImmunosensorsBenoît Piro0Steeve Reisberg1University Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, 75205 Paris CEDEX 13, FranceUniversity Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, 75205 Paris CEDEX 13, FranceImmunosensors have experienced a very significant growth in recent years, driven by the need for fast, sensitive, portable and easy-to-use devices to detect biomarkers for clinical diagnosis or to monitor organic pollutants in natural or industrial environments. Advances in the field of signal amplification using enzymatic reactions, nanomaterials such as carbon nanotubes, graphene and graphene derivatives, metallic nanoparticles (gold, silver, various oxides or metal complexes), or magnetic beads show how it is possible to improve collection, binding or transduction performances and reach the requirements for realistic clinical diagnostic or environmental control. This review presents these most recent advances; it focuses first on classical electrode substrates, then moves to carbon-based nanostructured ones including carbon nanotubes, graphene and other carbon materials, metal or metal-oxide nanoparticles, magnetic nanoparticles, dendrimers and, to finish, explore the use of ionic liquids. Analytical performances are systematically covered and compared, depending on the detection principle, but also from a chronological perspective, from 2012 to 2016 and early 2017.http://www.mdpi.com/1424-8220/17/4/794immunosensorselectrochemical sensorsnanoparticulescarbon nanotubesgrapheneenzymeredox probeantibodieshaptendendrimersmagnetic nanoparticlesionic liquidsELISAsandwich-type immunosensorscompetitive immunosensor |
| spellingShingle | Benoît Piro Steeve Reisberg Recent Advances in Electrochemical Immunosensors Sensors immunosensors electrochemical sensors nanoparticules carbon nanotubes graphene enzyme redox probe antibodies hapten dendrimers magnetic nanoparticles ionic liquids ELISA sandwich-type immunosensors competitive immunosensor |
| title | Recent Advances in Electrochemical Immunosensors |
| title_full | Recent Advances in Electrochemical Immunosensors |
| title_fullStr | Recent Advances in Electrochemical Immunosensors |
| title_full_unstemmed | Recent Advances in Electrochemical Immunosensors |
| title_short | Recent Advances in Electrochemical Immunosensors |
| title_sort | recent advances in electrochemical immunosensors |
| topic | immunosensors electrochemical sensors nanoparticules carbon nanotubes graphene enzyme redox probe antibodies hapten dendrimers magnetic nanoparticles ionic liquids ELISA sandwich-type immunosensors competitive immunosensor |
| url | http://www.mdpi.com/1424-8220/17/4/794 |
| work_keys_str_mv | AT benoitpiro recentadvancesinelectrochemicalimmunosensors AT steevereisberg recentadvancesinelectrochemicalimmunosensors |