Carbon Nanomaterials for Theranostic Use

Based on statistics from the National Cancer Institute in the US, the rate of new cases of cancer is 442.4 per 100,000 men and women per year, and more than one-third do not survive the disease. Cancer diagnosis and treatment are the most important challenges in modern medicine. The majority of canc...

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Main Authors: Izabela Kościk, Daniel Jankowski, Anna Jagusiak
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:C
Subjects:
Online Access:https://www.mdpi.com/2311-5629/8/1/3
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author Izabela Kościk
Daniel Jankowski
Anna Jagusiak
author_facet Izabela Kościk
Daniel Jankowski
Anna Jagusiak
author_sort Izabela Kościk
collection DOAJ
description Based on statistics from the National Cancer Institute in the US, the rate of new cases of cancer is 442.4 per 100,000 men and women per year, and more than one-third do not survive the disease. Cancer diagnosis and treatment are the most important challenges in modern medicine. The majority of cancer cases are diagnosed at an early stage. However, the possibility of simultaneous diagnosis and application of therapy (theranostics) will allow for acceleration and effectiveness of treatment. Conventional chemotherapy is not effective in reducing the chemoresistance and progression of various types of cancer. In addition, it causes side effects, which are mainly a result of incorrect drug distribution. Hence, new therapies are being explored as well as new drug delivery strategies. In this regard, nanotechnology has shown promise in the targeted delivery of therapeutics to cancer cells. This review looks at the latest advances in drug delivery-based diagnosis and therapy. Drug delivery nanosystems made of various types of carbon (graphene, fullerenes, and carbon nanotubes) are discussed. Their chemical properties, advantages, and disadvantages are explored, and these systems are compared with each other.
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spelling doaj.art-2e441b6c38c942b887e487350ba9b5062023-11-24T00:41:16ZengMDPI AGC2311-56292021-12-0181310.3390/c8010003Carbon Nanomaterials for Theranostic UseIzabela Kościk0Daniel Jankowski1Anna Jagusiak2Chair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, 31-034 Krakow, PolandFaculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, PolandChair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, 31-034 Krakow, PolandBased on statistics from the National Cancer Institute in the US, the rate of new cases of cancer is 442.4 per 100,000 men and women per year, and more than one-third do not survive the disease. Cancer diagnosis and treatment are the most important challenges in modern medicine. The majority of cancer cases are diagnosed at an early stage. However, the possibility of simultaneous diagnosis and application of therapy (theranostics) will allow for acceleration and effectiveness of treatment. Conventional chemotherapy is not effective in reducing the chemoresistance and progression of various types of cancer. In addition, it causes side effects, which are mainly a result of incorrect drug distribution. Hence, new therapies are being explored as well as new drug delivery strategies. In this regard, nanotechnology has shown promise in the targeted delivery of therapeutics to cancer cells. This review looks at the latest advances in drug delivery-based diagnosis and therapy. Drug delivery nanosystems made of various types of carbon (graphene, fullerenes, and carbon nanotubes) are discussed. Their chemical properties, advantages, and disadvantages are explored, and these systems are compared with each other.https://www.mdpi.com/2311-5629/8/1/3graphenegraphene family nanomaterials (GFNs)nano-graphene oxide (NGO)graphene oxide (GO)reduced graphene oxide (R-GO)photosensitizer (PS)
spellingShingle Izabela Kościk
Daniel Jankowski
Anna Jagusiak
Carbon Nanomaterials for Theranostic Use
C
graphene
graphene family nanomaterials (GFNs)
nano-graphene oxide (NGO)
graphene oxide (GO)
reduced graphene oxide (R-GO)
photosensitizer (PS)
title Carbon Nanomaterials for Theranostic Use
title_full Carbon Nanomaterials for Theranostic Use
title_fullStr Carbon Nanomaterials for Theranostic Use
title_full_unstemmed Carbon Nanomaterials for Theranostic Use
title_short Carbon Nanomaterials for Theranostic Use
title_sort carbon nanomaterials for theranostic use
topic graphene
graphene family nanomaterials (GFNs)
nano-graphene oxide (NGO)
graphene oxide (GO)
reduced graphene oxide (R-GO)
photosensitizer (PS)
url https://www.mdpi.com/2311-5629/8/1/3
work_keys_str_mv AT izabelakoscik carbonnanomaterialsfortheranosticuse
AT danieljankowski carbonnanomaterialsfortheranosticuse
AT annajagusiak carbonnanomaterialsfortheranosticuse