Genetic Dissection of Vps13 Regulation in Yeast Using Disease Mutations from Human Orthologs

The VPS13 family of proteins have emerged as key players in intracellular lipid transport and human health. Humans have four different <i>VPS13</i> orthologs, the dysfunction of which leads to different diseases. Yeast has a single <i>VPS13</i> gene, which encodes a protein t...

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Bibliographic Details
Main Authors: Jae-Sook Park, Nancy M. Hollingsworth, Aaron M. Neiman
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/12/6200