Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I
Neurofibromatosis type 1 (NF-1) is a genetic disease with autosomal dominant pattern which is associated with a large number of tumors especially of Gastro-Intestinal origin. These tumors have nurogenic or neuroendocrine origin (carcinoid tumors) and cause symptoms due to secretion of somatostatin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Dow University of Health Sciences
2015-08-01
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| Series: | Journal of the Dow University of Health Sciences |
| Online Access: | https://www.jduhs.com/index.php/jduhs/article/view/1463 |
| _version_ | 1797817548033490944 |
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| author | Abdul Qaiyoume Amini Naveed Ali Khan Jawed Ahmad Amjad Siraj Memon |
| author_facet | Abdul Qaiyoume Amini Naveed Ali Khan Jawed Ahmad Amjad Siraj Memon |
| author_sort | Abdul Qaiyoume Amini |
| collection | DOAJ |
| description |
Neurofibromatosis type 1 (NF-1) is a genetic disease with autosomal dominant pattern which is associated with a large number of tumors especially of Gastro-Intestinal origin. These tumors have nurogenic or neuroendocrine origin (carcinoid tumors) and cause symptoms due to secretion of somatostatin or local pressure effects. Here we report the case of a patient with Neurofibromatosis Type-1 who had a periampullary Nuroendocrine (Carcinoid) Tumor and presented with upper abdominalpain and mild jaundice. An initial diagnosis of carcinoma of head of pancreas was made based on CT scan and Wipple’s Pancreaticoduodenectomy performed. On histopathology, it was revealed as a neuroendocrine tumor with carcinoid features. Patient recovered well and became symptom free after surgery. This concludes that the pancreaticoduodenectomy
(Whippl’s procedure) is the current standard management in periampullary neuroendocrine tumors.
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| first_indexed | 2024-03-13T08:56:10Z |
| format | Article |
| id | doaj.art-2e496263b5804cf4827b7dd043bc3336 |
| institution | Directory Open Access Journal |
| issn | 1995-2198 2410-2180 |
| language | English |
| last_indexed | 2024-03-13T08:56:10Z |
| publishDate | 2015-08-01 |
| publisher | Dow University of Health Sciences |
| record_format | Article |
| series | Journal of the Dow University of Health Sciences |
| spelling | doaj.art-2e496263b5804cf4827b7dd043bc33362023-05-29T03:10:30ZengDow University of Health SciencesJournal of the Dow University of Health Sciences1995-21982410-21802015-08-0192Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type IAbdul Qaiyoume Amini0Naveed Ali Khan1Jawed Ahmad2Amjad Siraj Memon3Dow University of Health SciencesSurgical Unit V, Dow University of Health Sciences, Civil Hospital, Karachi, Pakistan.Surgical Unit V, Dow University of Health Sciences, Civil Hospital, Karachi, Pakistan.Surgical Unit V, Dow University of Health Sciences, Civil Hospital, Karachi, Pakistan. Neurofibromatosis type 1 (NF-1) is a genetic disease with autosomal dominant pattern which is associated with a large number of tumors especially of Gastro-Intestinal origin. These tumors have nurogenic or neuroendocrine origin (carcinoid tumors) and cause symptoms due to secretion of somatostatin or local pressure effects. Here we report the case of a patient with Neurofibromatosis Type-1 who had a periampullary Nuroendocrine (Carcinoid) Tumor and presented with upper abdominalpain and mild jaundice. An initial diagnosis of carcinoma of head of pancreas was made based on CT scan and Wipple’s Pancreaticoduodenectomy performed. On histopathology, it was revealed as a neuroendocrine tumor with carcinoid features. Patient recovered well and became symptom free after surgery. This concludes that the pancreaticoduodenectomy (Whippl’s procedure) is the current standard management in periampullary neuroendocrine tumors. https://www.jduhs.com/index.php/jduhs/article/view/1463 |
| spellingShingle | Abdul Qaiyoume Amini Naveed Ali Khan Jawed Ahmad Amjad Siraj Memon Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I Journal of the Dow University of Health Sciences |
| title | Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I |
| title_full | Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I |
| title_fullStr | Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I |
| title_full_unstemmed | Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I |
| title_short | Periampullary Neuroendocrine (Carcinoid) Tumor in a Patient with Neurofibromatosis Type I |
| title_sort | periampullary neuroendocrine carcinoid tumor in a patient with neurofibromatosis type i |
| url | https://www.jduhs.com/index.php/jduhs/article/view/1463 |
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