3D histopathology of stenotic aortic valve cusps using ex vivo microfocus computed tomography

3D histopathology of stenotic aortic valve cusps using ex vivo microfocus computed tomography

BackgroundCalcific aortic stenosis (AS) is the most prevalent heart valve disease in developed countries. The aortic valve cusps progressively thicken and the valve does not open fully due to the presence of calcifications. In vivo imaging, usually used for diagnosis, does not allow the visualizatio...

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Main Authors: Camille Pestiaux, Grzegorz Pyka, Louise Quirynen, David De Azevedo, Jean-Louis Vanoverschelde, Benoît Lengelé, David Vancraeynest, Christophe Beauloye, Greet Kerckhofs
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic stenosis
microstructural characterization
ex vivo imaging
microfocus computed tomography
3D histopathology
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1129990/full

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