Intubation without Muscle Relaxant: The Role of Sevoflurane
Background: Sevoflurane is preferred for induction of general anesthesia in pediatrics. We examined the minimum duration of sevoflurane administration resulting in most optimal intubation conditions. Methods: We included 75 children, aged 2-12 years, undergoing tonsillectomy under general anesthesi...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-10-01
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| Series: | Archives of Anesthesia and Critical Care |
| Subjects: | |
| Online Access: | https://aacc.tums.ac.ir/index.php/aacc/article/view/509 |
| _version_ | 1797902776239390720 |
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| author | Fatemeh Hajimohamadi Abolghasem Yoosefi Mehrdad Behzadi Nader Ali Nazemian Yazdi Hamed Abdollahi Afshar Etemadi-Aleagha Samira Parvizi Omran |
| author_facet | Fatemeh Hajimohamadi Abolghasem Yoosefi Mehrdad Behzadi Nader Ali Nazemian Yazdi Hamed Abdollahi Afshar Etemadi-Aleagha Samira Parvizi Omran |
| author_sort | Fatemeh Hajimohamadi |
| collection | DOAJ |
| description |
Background: Sevoflurane is preferred for induction of general anesthesia in pediatrics. We examined the minimum duration of sevoflurane administration resulting in most optimal intubation conditions.
Methods: We included 75 children, aged 2-12 years, undergoing tonsillectomy under general anesthesia at Amir-Alam Hospital. They were given midazolam 0.05 mg/kg and fentanyl 2 mic/kg IV, five minutes before induction with sevoflurane 8% in 60% N2O and 40% O2 with total gas flow of 10 lit/min via face mask for 90 seconds (group I), 120 sec (group II) or 150 sec (group III), randomly. After tracheal intubation, intubation condition was assessed using Steyn's modification of Helbo Hansen scoring system. The total scores were divided into clinically acceptable (≤10) or unacceptable (>10).
Results: There was no statistically significant difference among the three groups in demographic characteristics. Mean ± SD of intubation scores were 10.04±2.9, 8.12±3.2, and 5.64±1.15 in groups 1-3, respectively (P<0.001) with statistically significant differences between all three groups: between groups I and II (P=0.044), I and III (P<0.001), as well as II and III (P=0.004). Intubation conditions were acceptable in 11, 16, and 25 patients in each group, respectively (P<0.001).
Conclusion: Inhalation induction by sevoflurane 8% in 150s provides acceptable clinical situation for intubation in pediatrics.
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| first_indexed | 2024-04-10T09:23:00Z |
| format | Article |
| id | doaj.art-2e4e140ef039431d965f696c8161e0e0 |
| institution | Directory Open Access Journal |
| issn | 2423-5849 |
| language | English |
| last_indexed | 2024-04-10T09:23:00Z |
| publishDate | 2022-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Archives of Anesthesia and Critical Care |
| spelling | doaj.art-2e4e140ef039431d965f696c8161e0e02023-02-20T08:41:08ZengTehran University of Medical SciencesArchives of Anesthesia and Critical Care2423-58492022-10-019110.18502/aacc.v9i1.11944Intubation without Muscle Relaxant: The Role of SevofluraneFatemeh Hajimohamadi0Abolghasem Yoosefi1Mehrdad Behzadi2Nader Ali Nazemian Yazdi3Hamed Abdollahi4Afshar Etemadi-Aleagha5Samira Parvizi Omran6Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology, Amir A’lam Hospital, Tehran University of Medical Sciences, Tehran, Iran. Background: Sevoflurane is preferred for induction of general anesthesia in pediatrics. We examined the minimum duration of sevoflurane administration resulting in most optimal intubation conditions. Methods: We included 75 children, aged 2-12 years, undergoing tonsillectomy under general anesthesia at Amir-Alam Hospital. They were given midazolam 0.05 mg/kg and fentanyl 2 mic/kg IV, five minutes before induction with sevoflurane 8% in 60% N2O and 40% O2 with total gas flow of 10 lit/min via face mask for 90 seconds (group I), 120 sec (group II) or 150 sec (group III), randomly. After tracheal intubation, intubation condition was assessed using Steyn's modification of Helbo Hansen scoring system. The total scores were divided into clinically acceptable (≤10) or unacceptable (>10). Results: There was no statistically significant difference among the three groups in demographic characteristics. Mean ± SD of intubation scores were 10.04±2.9, 8.12±3.2, and 5.64±1.15 in groups 1-3, respectively (P<0.001) with statistically significant differences between all three groups: between groups I and II (P=0.044), I and III (P<0.001), as well as II and III (P=0.004). Intubation conditions were acceptable in 11, 16, and 25 patients in each group, respectively (P<0.001). Conclusion: Inhalation induction by sevoflurane 8% in 150s provides acceptable clinical situation for intubation in pediatrics. https://aacc.tums.ac.ir/index.php/aacc/article/view/509AnesthesiaInhalationSevofluraneTracheal intubation |
| spellingShingle | Fatemeh Hajimohamadi Abolghasem Yoosefi Mehrdad Behzadi Nader Ali Nazemian Yazdi Hamed Abdollahi Afshar Etemadi-Aleagha Samira Parvizi Omran Intubation without Muscle Relaxant: The Role of Sevoflurane Archives of Anesthesia and Critical Care Anesthesia Inhalation Sevoflurane Tracheal intubation |
| title | Intubation without Muscle Relaxant: The Role of Sevoflurane |
| title_full | Intubation without Muscle Relaxant: The Role of Sevoflurane |
| title_fullStr | Intubation without Muscle Relaxant: The Role of Sevoflurane |
| title_full_unstemmed | Intubation without Muscle Relaxant: The Role of Sevoflurane |
| title_short | Intubation without Muscle Relaxant: The Role of Sevoflurane |
| title_sort | intubation without muscle relaxant the role of sevoflurane |
| topic | Anesthesia Inhalation Sevoflurane Tracheal intubation |
| url | https://aacc.tums.ac.ir/index.php/aacc/article/view/509 |
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