Managing Wound Healing with a High-Risk Patient: A Case Report

Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as...

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Main Authors: Nikolai N. Potekaev, Olga B. Borzykh, German V. Medvedev, Marina M. Petrova, Elena I. Karpova, Maria A. Zatolokina, Mustafa Al-Zamil, Olga M. Demina, Ekaterina A. Narodova, Natalia A. Shnayder
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cosmetics
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Online Access:https://www.mdpi.com/2079-9284/9/2/28
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author Nikolai N. Potekaev
Olga B. Borzykh
German V. Medvedev
Marina M. Petrova
Elena I. Karpova
Maria A. Zatolokina
Mustafa Al-Zamil
Olga M. Demina
Ekaterina A. Narodova
Natalia A. Shnayder
author_facet Nikolai N. Potekaev
Olga B. Borzykh
German V. Medvedev
Marina M. Petrova
Elena I. Karpova
Maria A. Zatolokina
Mustafa Al-Zamil
Olga M. Demina
Ekaterina A. Narodova
Natalia A. Shnayder
author_sort Nikolai N. Potekaev
collection DOAJ
description Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as aesthetic dissatisfaction with the patient. This problem is especially important in aesthetic surgery. Patients who have come for beauty feel frustration, obtaining pathological scars. We have been dealing with the problem of wound healing after plastic surgery for about 10 years. Our approach includes the assessment of the risk of pathological wound healing and the treatment of high-risk patients. The risk assessment includes historical data on wound healing, signs of connective tissue dysfunction (especially patients with connective tissue dysplasia), and genetic polymorphisms of genes responsible for the structure of the components of the extracellular matrix of the skin. In the future, patients with a high risk of pathological scarring can be prescribed treatment after surgery. This article presents a clinical case in which we demonstrate our approach.
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spelling doaj.art-2e4ebbde137843228738c6b3313663352023-12-01T01:22:34ZengMDPI AGCosmetics2079-92842022-02-01922810.3390/cosmetics9020028Managing Wound Healing with a High-Risk Patient: A Case ReportNikolai N. Potekaev0Olga B. Borzykh1German V. Medvedev2Marina M. Petrova3Elena I. Karpova4Maria A. Zatolokina5Mustafa Al-Zamil6Olga M. Demina7Ekaterina A. Narodova8Natalia A. Shnayder9Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, RussiaDepartment of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, RussiaDepartment of Hand Surgery with Microsurgical Equipment, R. R. Vreden National Medical Research Centre for Traumatology and Orthopedics, 195427 Saint Petersburg, RussiaDepartment of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, RussiaDepartment of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, RussiaDepartment of Histology, Embryology, Cytology, Medical Faculty, Kursk State Medical University, 305014 Kursk, RussiaDepartment of Physiotherapy, Faculty of Continuing Medical Education, Peoples’ Friendship University of Russia, 117198 Moscow, RussiaDepartment of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, RussiaDepartment of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, RussiaDepartment of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, RussiaWound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as aesthetic dissatisfaction with the patient. This problem is especially important in aesthetic surgery. Patients who have come for beauty feel frustration, obtaining pathological scars. We have been dealing with the problem of wound healing after plastic surgery for about 10 years. Our approach includes the assessment of the risk of pathological wound healing and the treatment of high-risk patients. The risk assessment includes historical data on wound healing, signs of connective tissue dysfunction (especially patients with connective tissue dysplasia), and genetic polymorphisms of genes responsible for the structure of the components of the extracellular matrix of the skin. In the future, patients with a high risk of pathological scarring can be prescribed treatment after surgery. This article presents a clinical case in which we demonstrate our approach.https://www.mdpi.com/2079-9284/9/2/28wound healingscarsplastic surgeryrejuvenation
spellingShingle Nikolai N. Potekaev
Olga B. Borzykh
German V. Medvedev
Marina M. Petrova
Elena I. Karpova
Maria A. Zatolokina
Mustafa Al-Zamil
Olga M. Demina
Ekaterina A. Narodova
Natalia A. Shnayder
Managing Wound Healing with a High-Risk Patient: A Case Report
Cosmetics
wound healing
scars
plastic surgery
rejuvenation
title Managing Wound Healing with a High-Risk Patient: A Case Report
title_full Managing Wound Healing with a High-Risk Patient: A Case Report
title_fullStr Managing Wound Healing with a High-Risk Patient: A Case Report
title_full_unstemmed Managing Wound Healing with a High-Risk Patient: A Case Report
title_short Managing Wound Healing with a High-Risk Patient: A Case Report
title_sort managing wound healing with a high risk patient a case report
topic wound healing
scars
plastic surgery
rejuvenation
url https://www.mdpi.com/2079-9284/9/2/28
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