Identification and Characterization of Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma Using the SORE6 Reporter

Identification and Characterization of Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma Using the SORE6 Reporter

Transcription factors Sox2 and Oct4 are essential in maintaining the pluripotency of embryonic stem cells and conferring stemness in cancer stem-like (CSL) cells. SORE6, an in-vitro reporter system, was designed to quantify the transcription activity of Sox2/Oct4 and identify CSL cells in non-hemato...

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Bibliographic Details
Main Authors:	Jing Li, Moinul Haque, Chuquan Shang, Bardes Hassan, Dongzhe Liu, Will Chen, Raymond Lai
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Current Issues in Molecular Biology
Subjects:	anaplastic large cell lymphoma SORE6 cancer stem-like cells Sox2 Oct4
Online Access:	https://www.mdpi.com/1467-3045/43/2/41

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